{"id":"W4319432110","doi":"10.4049/jimmunol.206.supp.51.13","title":"ICOS is critical for T follicular regulatory cell differentiation","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; McGill University; Montreal Clinical Research Institute","funders":"","keywords":"Germinal center; FOXP3; CXCR5; Immunology; Antibody; Biology; B cell; Autoantibody; Follicular phase; T cell; Cell biology; Immune system; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001017977,0.000316155,0.0001658635,0.0002173593,0.0001921679,0.0003807028,0.0002500768,0.0002957859,0.002083845],"category_scores_gemma":[0.0001633957,0.0001189338,0.0001675612,0.00008203698,0.0002529559,0.0001620455,0.0001975443,0.000472136,0.0006505195],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002524343,"about_ca_system_score_gemma":0.0001882609,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004220212,"about_ca_topic_score_gemma":0.0004458914,"domain_scores_codex":[0.9998336,0.00001648876,0.00001414375,0.00004446459,0.00003822085,0.00005299057],"domain_scores_gemma":[0.9995298,0.0000489973,0.0001671393,0.00004364815,0.00004321144,0.0001671201],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005605272,0.000009055953,0.0002553784,0.00001575193,0.00000123252,0.0000619475,0.000005151509,0.00001440003,0.9990231,0.00008621056,0.00003357559,0.0004381018],"study_design_scores_gemma":[0.00002239782,0.0001510712,0.0163769,0.00001707372,0.00002024215,0.0006554178,0.00005442257,0.0006949116,0.9762407,0.0001140193,0.005647318,0.000005517782],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9896801,0.002230447,0.004306514,0.00009012255,0.00008474567,0.00001977869,0.0005211687,0.0001939352,0.00287313],"genre_scores_gemma":[0.9958476,0.0003167877,0.001324487,0.00005694496,0.00002338615,0.00001378796,0.0005656502,0.00005820993,0.001793102],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002083845,"threshold_uncertainty_score":0.006971121,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01119986497318509,"score_gpt":0.2421709362792736,"score_spread":0.2309710713060885,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}