{"id":"W4319432206","doi":"10.4049/jimmunol.206.supp.97.04","title":"MER Tyrosine Kinase Mediates Efferocytosis Through a Novel β2 Integrin-Activating Signalling Pathway","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Phagocytosis and Immune Regulation","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"","keywords":"MERTK; Efferocytosis; Cell biology; Integrin; GAS6; Signal transduction; Receptor tyrosine kinase; Tyrosine kinase; Biology; Integrin alpha M; Chemistry; Receptor; Macrophage; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001097175,0.0003962022,0.0002164154,0.0001202942,0.0002186426,0.0004169736,0.0001760794,0.0004359731,0.001639113],"category_scores_gemma":[0.00008056837,0.0001145772,0.0003117863,0.00009525292,0.00009765429,0.0002766523,0.0002540009,0.0005245126,0.0007277573],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003587033,"about_ca_system_score_gemma":0.0001209504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002097967,"about_ca_topic_score_gemma":0.0002250438,"domain_scores_codex":[0.9998728,0.00001789002,0.000007493933,0.00002673027,0.00002864623,0.00004649019],"domain_scores_gemma":[0.9999554,0.000007031348,0.00001173088,0.00000478453,0.000009513205,0.00001153828],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006368502,0.00001846435,0.0001359105,0.00004697268,0.000004228436,0.0001864024,0.00001108575,0.00008426064,0.99822,0.0004224774,0.0001028251,0.0007036551],"study_design_scores_gemma":[0.00005774466,0.0002847968,0.01115775,0.00002358626,0.00002717751,0.00167497,0.00009505606,0.007042134,0.9678864,0.0005209664,0.01121261,0.00001677084],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.982825,0.003411376,0.007263734,0.0002875542,0.00009151033,0.00004319077,0.0004487518,0.0001425406,0.005486323],"genre_scores_gemma":[0.9931698,0.001061626,0.001693273,0.000106566,0.0000205069,0.00003183783,0.0004572424,0.000008084601,0.003451088],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001639113,"threshold_uncertainty_score":0.005483329,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02480938171474192,"score_gpt":0.2489652665845406,"score_spread":0.2241558848697986,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}