{"id":"W4319432374","doi":"10.4049/jimmunol.206.supp.17.30","title":"ATG16L1 deficiency exacerbates acute small intestinal epithelial damage.","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"ATG16L1; Autophagy; Paneth cell; Crypt; Apoptosis; Biology; Programmed cell death; Tumor necrosis factor alpha; Intestinal mucosa; Cancer research; Cytokine; Immune system; Immunology; Inflammatory bowel disease; Medicine; Internal medicine; Endocrinology; Disease; Small intestine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002341177,0.0006950963,0.00059018,0.0004554288,0.0001909693,0.0003108896,0.0002051786,0.000694159,0.002926925],"category_scores_gemma":[0.0001389763,0.0003577752,0.0004486071,0.0002317112,0.0004106422,0.0003714339,0.0003581052,0.001430909,0.000615047],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003109892,"about_ca_system_score_gemma":0.0002074686,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002688796,"about_ca_topic_score_gemma":0.000629517,"domain_scores_codex":[0.9997393,0.00004668773,0.00003699469,0.00005263966,0.00004508657,0.00007926438],"domain_scores_gemma":[0.9995911,0.00003112351,0.0001541634,0.00003135896,0.00001820585,0.0001740253],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001006943,0.0001819217,0.0006803988,0.0001149963,0.000009856676,0.0001835807,0.00002681537,0.00003808307,0.9966844,0.00004527318,0.00006257848,0.0009651967],"study_design_scores_gemma":[0.0002581167,0.01173578,0.03682902,0.00007626787,0.00007797575,0.002707246,0.000222988,0.0007631094,0.9428053,0.0001849616,0.00432314,0.00001606042],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971488,0.001133824,0.0004004244,0.0001289324,0.0000409051,0.00004789082,0.0004031032,0.00007011602,0.000625946],"genre_scores_gemma":[0.9948736,0.0009034627,0.0006481174,0.0001143235,0.00001769636,0.00006493773,0.000438418,0.00002459855,0.002914955],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002926925,"threshold_uncertainty_score":0.009791493,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01679907502361837,"score_gpt":0.2720514735434987,"score_spread":0.2552523985198804,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}