{"id":"W4319433545","doi":"10.4049/jimmunol.206.supp.111.13","title":"Transcriptional regulation of type 2 innate lymphoid cells and precursors by interleukin-7 receptor signalling","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Innate lymphoid cell; Biology; GATA3; Interleukin 22; Immunology; Progenitor cell; Immune system; Innate immune system; Epigenetics; Lymphopoiesis; Interleukin-7 receptor; Transcription factor; Cell biology; Stem cell; IL-2 receptor; Interleukin; T cell; Cytokine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000128254,0.0002723285,0.0001986695,0.0002184211,0.0001773419,0.000602363,0.0002016893,0.0002827678,0.001992475],"category_scores_gemma":[0.0001194995,0.0001881968,0.000343344,0.0001472689,0.00016873,0.0002092317,0.0002895868,0.0005803959,0.0008124398],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003177941,"about_ca_system_score_gemma":0.0002341698,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004561672,"about_ca_topic_score_gemma":0.001098238,"domain_scores_codex":[0.99977,0.00002243037,0.00001282716,0.0000742902,0.00006495298,0.00005548881],"domain_scores_gemma":[0.9998772,0.00001871525,0.00003432498,0.00001280861,0.00002560958,0.00003131405],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006721075,0.000009146359,0.001016109,0.00004461018,0.000004275128,0.00005389761,0.00002450736,0.00005083175,0.9970967,0.0001814451,0.0001165017,0.001334884],"study_design_scores_gemma":[0.00002892201,0.0002196533,0.08653431,0.00005568301,0.00003435523,0.000565213,0.0003216259,0.002240007,0.893397,0.0003280962,0.01625585,0.00001918733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737759,0.00720051,0.009112286,0.0002740999,0.000140714,0.00005893004,0.003251908,0.0002272984,0.005958345],"genre_scores_gemma":[0.980728,0.001644531,0.005036681,0.0002795433,0.00004808471,0.0000913054,0.004405324,0.00007157293,0.007694904],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001992475,"threshold_uncertainty_score":0.006665468,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016502219853661,"score_gpt":0.2041340679222767,"score_spread":0.1939690457237401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}