{"id":"W4319433545","doi":"10.4049/jimmunol.206.supp.111.13","title":"Transcriptional regulation of type 2 innate lymphoid cells and precursors by interleukin-7 receptor signalling","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"IL-33, ST2, and ILC Pathways","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Innate lymphoid cell; Biology; GATA3; Interleukin 22; Immunology; Progenitor cell; Immune system; Innate immune system; Epigenetics; Lymphopoiesis; Interleukin-7 receptor; Transcription factor; Cell biology; Stem cell; IL-2 receptor; Interleukin; T cell; Cytokine; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000511384,0.0001264162,0.000321921,0.00009001728,0.0001064599,0.000006116297,0.0002057868,0.0002110237,0.000408453],"category_scores_gemma":[0.00009295884,0.00009235903,0.00007656772,0.0001509973,0.0003355436,0.0001058223,0.00004190854,0.0003439175,0.00003186082],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003873367,"about_ca_system_score_gemma":0.0001774943,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001535377,"about_ca_topic_score_gemma":0.00000454091,"domain_scores_codex":[0.998614,0.000526225,0.0005157852,0.0001028524,0.0000462877,0.000194913],"domain_scores_gemma":[0.9988153,0.0002167662,0.0004088189,0.0001339487,0.0004119043,0.00001327132],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008632521,0.00008310169,0.00007349866,0.00001554483,0.0003745896,0.000001688859,0.001839532,0.0000217649,0.991984,0.0003906627,0.002361641,0.001990734],"study_design_scores_gemma":[0.001280195,0.000593969,0.0007169441,0.00007667748,0.00009310165,0.0007702252,0.0008438287,0.000004095694,0.9405714,0.0005221048,0.0544333,0.00009414735],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9784009,0.01898052,0.0004225209,0.000276097,0.001461577,0.0000582103,0.0001501349,0.000007402929,0.0002426553],"genre_scores_gemma":[0.994397,0.004161124,0.0001472248,0.00007908062,0.00004142116,6.22158e-7,0.00004341218,0.00001207153,0.001118065],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05207166,"threshold_uncertainty_score":0.4472274,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016502219853661,"score_gpt":0.2041340679222767,"score_spread":0.1939690457237401,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}