{"id":"W4319433952","doi":"10.4049/jimmunol.206.supp.23.15","title":"Human and mouse mast cells express surface PrP that is shed upon activation and affects degranulation","year":2021,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta; National Research Council Canada","funders":"","keywords":"Degranulation; Mast cell; Immune system; Cell biology; Inflammation; Immunoglobulin E; Biology; Knockout mouse; Receptor; Immunology; Antibody; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001440472,0.000245911,0.0001606196,0.0001762057,0.00008539103,0.0001484149,0.0001105483,0.000278776,0.001548945],"category_scores_gemma":[0.000100629,0.000103744,0.0002710996,0.0001547463,0.0001050638,0.0001209348,0.0001181016,0.0002821481,0.0004442269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000104397,"about_ca_system_score_gemma":0.00003620772,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001398949,"about_ca_topic_score_gemma":0.0001334675,"domain_scores_codex":[0.9998741,0.0000215286,0.0000113386,0.0000274812,0.00002929149,0.00003622436],"domain_scores_gemma":[0.9999316,0.00001927744,0.00001900935,0.00001026643,0.00000757077,0.00001234816],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008381012,0.000007131881,0.0002038979,0.00001440026,0.000001918843,0.0001056781,0.000008065742,0.0000073726,0.9992311,0.00001039463,0.00001444016,0.0003116654],"study_design_scores_gemma":[0.00004363081,0.0009618819,0.03702586,0.00001200789,0.00003489446,0.003042897,0.00006620984,0.0006374712,0.9554799,0.00005912928,0.002629379,0.000006791276],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996351,0.001702696,0.0008115767,0.00004256601,0.00001635585,0.0000241822,0.0004123762,0.00002864039,0.0006104588],"genre_scores_gemma":[0.9959249,0.000787924,0.001093542,0.00004677261,0.00001503859,0.00004274808,0.0008397448,0.00000676922,0.001242403],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001548945,"threshold_uncertainty_score":0.00518173,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01312887276900677,"score_gpt":0.221123066174282,"score_spread":0.2079941934052752,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}