{"id":"W4319456968","doi":"10.1056/nejmoa2210699","title":"Phase 2 Trial of Difelikefalin in Notalgia Paresthetica","year":2023,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Dermatology and Skin Diseases","field":"Medicine","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Innovaderm (Canada)","funders":"","keywords":"Medicine; Placebo; Confidence interval; Quality of life (healthcare); Randomized controlled trial; Clinical trial; Physical therapy; Anesthesia; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001414148,0.001975655,0.002979137,0.0005477113,0.0004087098,0.0007430384,0.001027172,0.002017064,0.01136114],"category_scores_gemma":[0.001596083,0.0006737505,0.001289291,0.000454238,0.0007079783,0.000813238,0.0003736136,0.002407532,0.001289739],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006700841,"about_ca_system_score_gemma":0.001525693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006252627,"about_ca_topic_score_gemma":0.001322423,"domain_scores_codex":[0.999471,0.000239655,0.00002946192,0.00008531709,0.00005251453,0.0001221128],"domain_scores_gemma":[0.9993652,0.000144987,0.0001477402,0.00006781195,0.0000753514,0.0001990156],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.9196853,0.02932868,0.0007445675,0.001301176,0.0005918271,0.0001681342,0.00009877438,0.0004794197,0.01251501,0.0001920318,0.002421052,0.03247401],"study_design_scores_gemma":[0.9023898,0.09441008,0.001201842,0.00002777085,0.0001026275,0.0000822557,0.00001275543,0.0002044793,0.0005102229,0.00007515368,0.0009731101,0.000009884772],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9738041,0.004284171,0.001170557,0.001139547,0.0007206486,0.01334775,0.002249699,0.0002617587,0.003021874],"genre_scores_gemma":[0.9483737,0.00435263,0.003402253,0.003186433,0.0007541408,0.02677158,0.004310904,0.00005493582,0.008793421],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01136114,"threshold_uncertainty_score":0.03800684,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03091209032543232,"score_gpt":0.351326629752397,"score_spread":0.3204145394269646,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}