{"id":"W4319460459","doi":"10.1002/advs.202205713","title":"Small Molecule‐Templated DNA Hydrogel with Record Stiffness Integrates and Releases DNA Nanostructures and Gene Silencing Nucleic Acids","year":2023,"lang":"en","type":"article","venue":"Advanced Science","topic":"Advanced biosensing and bioanalysis techniques","field":"Biochemistry, Genetics and Molecular Biology","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Fonds de recherche du Québec – Nature et technologies; Killam Trusts; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs; Canada Council for the Arts","keywords":"Nucleic acid; DNA; Gene silencing; Nanotechnology; DNA nanotechnology; Nanostructure; Chemistry; Gene; Materials science; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001764886,0.0002368777,0.0002033632,0.0001574863,0.0003616517,0.00007190904,0.0002198225,0.00008936783,5.091089e-7],"category_scores_gemma":[0.0001979727,0.0001770276,0.00003107411,0.0008257482,0.0008514631,0.00002658492,0.0001987806,0.000100762,8.51796e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001761718,"about_ca_system_score_gemma":0.00007396159,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002443384,"about_ca_topic_score_gemma":0.00008083269,"domain_scores_codex":[0.9984374,0.00002306698,0.0001859369,0.0007752803,0.0001846667,0.0003936185],"domain_scores_gemma":[0.9992238,0.00002623955,0.0001107424,0.0003410713,0.0001547292,0.0001433747],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006975316,0.000007530689,0.0006412126,0.00001035189,0.00001287308,0.00001535161,0.00003733736,0.00002425496,0.9803347,0.00001876463,0.00001134608,0.0188165],"study_design_scores_gemma":[0.0002484317,0.0002752499,0.00401915,0.00006050353,0.00002055715,0.0000726792,0.0002273553,0.0004342219,0.9938446,0.0003091025,0.0001971114,0.0002909853],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9987872,0.0002739891,0.000497534,0.00006822398,0.00004408962,0.0001348478,0.00001422345,0.0001299267,0.00004998772],"genre_scores_gemma":[0.9891291,0.0005792683,0.00995596,0.0001505955,0.00002723453,0.000008779622,0.0000320203,0.00002193717,0.00009514946],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01852551,"threshold_uncertainty_score":0.7218975,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009394555206257494,"score_gpt":0.2452192942397259,"score_spread":0.2358247390334684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}