{"id":"W4319593697","doi":"10.1038/s41389-023-00450-w","title":"Negligible role of TRAIL death receptors in cell death upon endoplasmic reticulum stress in B-cell malignancies","year":2023,"lang":"en","type":"article","venue":"Oncogenesis","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"Horizon 2020 Framework Programme; European Commission","keywords":"Endoplasmic reticulum; Programmed cell death; Receptor; Cell biology; Cell; Apoptosis; Biology; Medicine; Internal medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001746068,0.0001432957,0.0001548971,0.0002097213,0.0001443068,0.0003604084,0.0001004825,0.0002247686,0.0008655116],"category_scores_gemma":[0.0001501462,0.00007775661,0.0001422737,0.0001317221,0.0002295196,0.0002355593,0.0002723807,0.0003763436,0.0002773405],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002505248,"about_ca_system_score_gemma":0.0002345888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002527705,"about_ca_topic_score_gemma":0.000315179,"domain_scores_codex":[0.9998573,0.00003552075,0.00001898245,0.00001920342,0.00003783047,0.00003115547],"domain_scores_gemma":[0.9998791,0.00001863833,0.00002956939,0.00001723343,0.00001415498,0.0000411908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000239117,0.00002013157,0.0007068214,0.00004418291,0.000005228008,0.0001046612,0.00002386719,0.0000644418,0.99597,0.0002289445,0.00002207319,0.002570609],"study_design_scores_gemma":[0.00003987019,0.0007001245,0.01099029,0.00001611593,0.00003652231,0.001534271,0.00009218225,0.0004863761,0.9804071,0.0002184187,0.00547169,0.000007127732],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932393,0.003781442,0.001330313,0.00008969044,0.00001458924,0.00001461699,0.0001227224,0.0000339924,0.001373413],"genre_scores_gemma":[0.997659,0.0006696215,0.000587893,0.00003053454,0.00000241903,0.00000935785,0.0001311605,0.000005158674,0.0009049947],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008655116,"threshold_uncertainty_score":0.002895474,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009431183462877581,"score_gpt":0.2335512499857148,"score_spread":0.2241200665228372,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}