{"id":"W4319593901","doi":"10.1038/s41422-023-00780-9","title":"Transcription initiation by the ERRs: no ligand but two activation pathways","year":2023,"lang":"en","type":"article","venue":"Cell Research","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":4,"is_retracted":false,"has_abstract":false,"ca_institutions":"McGill University; McGill University Health Centre","funders":"","keywords":"Transcription (linguistics); Transcription factor; Computational biology; Biology; Cell biology; Genetics; Gene; Philosophy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006854511,0.00007079061,0.00004994854,0.00004890754,0.0002212205,0.00006372653,0.0001894321,0.00008872728,0.00001480257],"category_scores_gemma":[0.0000604484,0.00005777386,0.00003815403,0.0001976243,0.00006039206,0.00000439923,0.00006620719,0.0001582001,0.0001720182],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002548969,"about_ca_system_score_gemma":0.00007055693,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003573127,"about_ca_topic_score_gemma":0.00001533653,"domain_scores_codex":[0.9990768,0.0001081848,0.0001147688,0.0002074128,0.0002353888,0.0002574112],"domain_scores_gemma":[0.9994749,0.00003664739,0.00002833849,0.0002468344,0.0001702988,0.00004301017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002282231,0.00002408906,0.00006994291,0.00001717377,0.000005657012,5.019342e-7,0.0001140715,0.00007789805,0.9821419,0.0000577588,0.01602343,0.001444796],"study_design_scores_gemma":[0.0003888731,0.0001501402,0.0008045301,0.000006792339,0.000002624649,9.405805e-7,0.0003618165,0.00356057,0.9718413,0.000402639,0.02239064,0.00008915953],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9921514,0.0001001091,0.0003453323,0.0003017034,0.00008077111,0.0002114786,0.00002839636,0.00001424194,0.006766585],"genre_scores_gemma":[0.9953705,0.000476034,0.00003230275,0.00006222682,0.0001857548,0.00004268224,0.0006937209,0.0000184935,0.003118276],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01030059,"threshold_uncertainty_score":0.235595,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04779061005350185,"score_gpt":0.3104571759979549,"score_spread":0.262666565944453,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}