{"id":"W4319599785","doi":"10.3390/v15020463","title":"Stability of APOBEC3F in the Presence of the APOBEC3 Antagonist HIV-1 Vif Increases at the Expense of Co-Expressed APOBEC3H Haplotype I","year":2023,"lang":"en","type":"article","venue":"Viruses","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research","keywords":"APOBEC3G; Haplotype; Biology; Ubiquitin; Proteasome; Cytidine deaminase; Enzyme; Restriction enzyme; Degradation (telecommunications); Ubiquitin ligase; Human immunodeficiency virus (HIV); Cell biology; Genetics; Virology; Biochemistry; Gene; Genotype","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008692475,0.000125711,0.0001650478,0.0001280118,0.0001880239,0.0003359687,0.0001558304,0.0002451999,0.001350853],"category_scores_gemma":[0.0002581287,0.00009037462,0.0001735347,0.000109282,0.0001161269,0.0002246671,0.0001203951,0.0004381372,0.0002522558],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003160525,"about_ca_system_score_gemma":0.0001618642,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002345898,"about_ca_topic_score_gemma":0.001878408,"domain_scores_codex":[0.999855,0.00001851306,0.000009452051,0.0000402452,0.00003854445,0.0000383074],"domain_scores_gemma":[0.9998518,0.00002236193,0.00003834108,0.00001675896,0.00002763217,0.00004302203],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004913171,0.0000110006,0.0006121343,0.00001046956,0.000006558038,0.0000297007,0.00001942543,0.00003334737,0.9984061,0.00005833761,0.00003137222,0.0007324199],"study_design_scores_gemma":[0.00000803464,0.0002160775,0.02251343,0.000008770973,0.0000233019,0.0004961994,0.0000943475,0.002357268,0.971777,0.00009945021,0.002394797,0.00001144519],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9968259,0.0009010707,0.001134832,0.00004764711,0.00001010711,0.00000582337,0.0001336949,0.00002455467,0.0009164147],"genre_scores_gemma":[0.9974619,0.0001705739,0.000704702,0.00002987161,0.000003586545,0.000008101417,0.000275214,0.000009919402,0.00133617],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002345898,"threshold_uncertainty_score":0.00466454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04836240558676792,"score_gpt":0.3083795900938482,"score_spread":0.2600171845070803,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}