{"id":"W4319600886","doi":"10.3390/cancers15041051","title":"A Novel Blood Proteomic Signature for Prostate Cancer","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Blood Cancer UK; Medical Research Council; Bloodwise; Punjab Educational Endowment Fund; Cancer Research UK","keywords":"Prostate cancer; Medicine; Prostate; Oncology; Cancer; Internal medicine; Proteomics; Bioinformatics; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004091575,0.0003628776,0.0003350894,0.001377983,0.000240367,0.0008438954,0.0002019699,0.0004434281,0.0009843042],"category_scores_gemma":[0.001038115,0.0001044029,0.0002670552,0.001015459,0.0001946143,0.0002594661,0.0004593037,0.0004348464,0.0003919523],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002462561,"about_ca_system_score_gemma":0.0002848149,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00078824,"about_ca_topic_score_gemma":0.0008833038,"domain_scores_codex":[0.9997253,0.00003914819,0.00001997398,0.00008704046,0.00009626555,0.00003221732],"domain_scores_gemma":[0.9996734,0.00007144042,0.0001006523,0.00002249208,0.00007891062,0.00005317281],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001828975,0.0002346186,0.3128428,0.0007460357,0.0004744858,0.001345905,0.000248452,0.002628044,0.529779,0.001146186,0.005679975,0.1430456],"study_design_scores_gemma":[0.00006377898,0.0007746076,0.7222642,0.0001441967,0.0004103546,0.009846881,0.000229488,0.04422804,0.1990278,0.002761629,0.02014636,0.000102714],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9640834,0.005950373,0.01967834,0.0005042999,0.0001075275,0.0001044524,0.00533442,0.000713491,0.003523669],"genre_scores_gemma":[0.9841613,0.0007647828,0.01147839,0.0002943036,0.00006311474,0.00003034019,0.002381768,0.00003027643,0.00079562],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001377983,"threshold_uncertainty_score":0.003292859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553398222870384,"score_gpt":0.2973278587911704,"score_spread":0.2817938765624665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}