{"id":"W4319600886","doi":"10.3390/cancers15041051","title":"A Novel Blood Proteomic Signature for Prostate Cancer","year":2023,"lang":"en","type":"article","venue":"Cancers","topic":"Advanced Proteomics Techniques and Applications","field":"Chemistry","cited_by":20,"is_retracted":false,"has_abstract":true,"ca_institutions":"SickKids Foundation","funders":"Blood Cancer UK; Medical Research Council; Bloodwise; Punjab Educational Endowment Fund; Cancer Research UK","keywords":"Prostate cancer; Medicine; Prostate; Oncology; Cancer; Internal medicine; Proteomics; Bioinformatics; Computational biology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00004356816,0.0001244297,0.0001175709,0.00003060314,0.0001200309,0.00001754428,0.0001624513,0.0001014058,0.0001438035],"category_scores_gemma":[0.00001745608,0.0001236671,0.00006619757,0.0002170418,0.00004551708,0.00004734729,0.00003642332,0.0001554737,0.000008784485],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003300224,"about_ca_system_score_gemma":0.0003010569,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001411796,"about_ca_topic_score_gemma":0.00003260271,"domain_scores_codex":[0.9992054,0.000001048526,0.0001311808,0.0003019575,0.00007572497,0.0002847546],"domain_scores_gemma":[0.9995311,0.00002129836,0.00008322397,0.0002425546,0.0000613414,0.00006043361],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003261384,0.000006989669,0.00007735488,0.0001421253,0.00002848071,6.804306e-7,0.00008566799,0.002329002,0.9866179,0.0006137518,0.005562109,0.004503381],"study_design_scores_gemma":[0.0006825057,0.00001544236,0.00001057982,0.0000802557,0.00003126041,0.000001667305,0.00005458596,0.001719811,0.9178692,0.002862515,0.07645119,0.0002209545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9494266,0.0009061575,0.03054136,0.002840156,0.0002228601,0.003860872,0.004633151,0.002440095,0.005128733],"genre_scores_gemma":[0.719569,0.002407073,0.1123235,0.001034723,0.001428329,0.08494358,0.0008925342,0.0003683108,0.07703295],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2298576,"threshold_uncertainty_score":0.5042998,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01553398222870384,"score_gpt":0.2973278587911704,"score_spread":0.2817938765624665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}