{"id":"W4319602604","doi":"10.3389/fmed.2023.1138464","title":"First-line therapy in drug reaction with eosinophilia and systemic symptoms (DReSS): Thinking beyond corticosteroids","year":2023,"lang":"en","type":"article","venue":"Frontiers in Medicine","topic":"Drug-Induced Adverse Reactions","field":"Medicine","cited_by":13,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; Sunnybrook Hospital; University of Toronto","funders":"","keywords":"Eosinophilia; Medicine; Systemic therapy; Drug; Dermatology; Pharmacology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.004956529,0.0006684586,0.001692452,0.0008841041,0.0005782527,0.002322702,0.0009354321,0.003051192,0.002231235],"category_scores_gemma":[0.005249618,0.0002555567,0.0009331413,0.0003615432,0.001978848,0.004967847,0.001118877,0.009764266,0.001042986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001782609,"about_ca_system_score_gemma":0.001513269,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001177514,"about_ca_topic_score_gemma":0.003691401,"domain_scores_codex":[0.9982779,0.0008337888,0.0002136965,0.0001366091,0.000416181,0.0001218456],"domain_scores_gemma":[0.9930179,0.004212902,0.0008051076,0.0001700154,0.001199096,0.0005950673],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0007751901,0.0003621194,0.004877955,0.005983584,0.0003412273,0.002052038,0.000677801,0.0009789013,0.00292113,0.0229416,0.2133439,0.7447445],"study_design_scores_gemma":[0.0005939903,0.001779718,0.01069236,0.01883075,0.000834215,0.01035978,0.002476369,0.003239392,0.001866554,0.08177827,0.8673063,0.0002422249],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.004804397,0.7295431,0.006365102,0.2320924,0.01453487,0.00004524119,0.00008288513,0.000161567,0.01237045],"genre_scores_gemma":[0.1090696,0.6195273,0.01337068,0.1752078,0.07477201,0.0001185747,0.0001514195,0.00008494017,0.007697592],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.004956529,"threshold_uncertainty_score":0.02621293,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01490355962973665,"score_gpt":0.2641398822695622,"score_spread":0.2492363226398255,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}