{"id":"W4319656695","doi":"10.1080/21645515.2023.2172925","title":"Portrait of an autologous cancer vaccine: Then and now","year":2023,"lang":"en","type":"article","venue":"Human Vaccines & Immunotherapeutics","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"AXYS Technologies (Canada)","funders":"","keywords":"Medicine; Melanoma; Immunology; Immunotherapy; Immune system; Cancer vaccine; Cancer; Antigen; CD8; T cell; Cyclophosphamide; Clinical trial; Cancer research; Chemotherapy; Pathology; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006179864,0.0003449571,0.0002511557,0.0006629783,0.0005149071,0.002117197,0.0003488364,0.001050972,0.002801434],"category_scores_gemma":[0.000472431,0.0001438167,0.0002799311,0.0003791054,0.001457151,0.002627902,0.0005933156,0.002390465,0.001355559],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001180626,"about_ca_system_score_gemma":0.0007611437,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006642045,"about_ca_topic_score_gemma":0.0007712852,"domain_scores_codex":[0.9998239,0.00004826267,0.00001384468,0.00003293115,0.0000590071,0.00002218319],"domain_scores_gemma":[0.9998348,0.00004378605,0.00002038919,0.00001840766,0.00004238268,0.00004018448],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"theoretical_or_conceptual","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0004624844,0.0002651441,0.003162377,0.001805201,0.0000429779,0.001714092,0.001622336,0.00125675,0.08699778,0.4996091,0.04109389,0.361968],"study_design_scores_gemma":[0.00001470644,0.0001583972,0.001019028,0.0002627738,0.00001286907,0.00139663,0.000265743,0.0003317346,0.005089572,0.03010996,0.9613284,0.0000101618],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.03653403,0.5970844,0.03006057,0.08499487,0.005418357,0.000135357,0.0005200593,0.0002303357,0.245022],"genre_scores_gemma":[0.3129809,0.4340773,0.0318096,0.03562384,0.004235213,0.0003305609,0.001028427,0.0001515982,0.1797625],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002801434,"threshold_uncertainty_score":0.009371758,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0238657141158829,"score_gpt":0.3040810280545768,"score_spread":0.2802153139386939,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}