{"id":"W4319765818","doi":"10.1038/s12276-023-00945-x","title":"ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions","year":2023,"lang":"en","type":"article","venue":"Experimental & Molecular Medicine","topic":"Endoplasmic Reticulum Stress and Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"BC Children's Hospital; University of British Columbia","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Korea Basic Science Institute; National Research Foundation","keywords":"Endoplasmic reticulum; Apoptosis; Cell biology; Unfolded protein response; Inflammation; Chemistry; Biology; Immunology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001011421,0.0004112794,0.0003394867,0.0001396096,0.000162828,0.00002951739,0.0003099079,0.0002244639,0.0005162513],"category_scores_gemma":[0.0001024792,0.000378741,0.0001637486,0.0002803116,0.0004039064,0.0000106327,0.0002297341,0.000188695,0.0002750676],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004059838,"about_ca_system_score_gemma":0.00009647504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001271875,"about_ca_topic_score_gemma":0.00000958404,"domain_scores_codex":[0.997646,0.000144777,0.000433041,0.0007387457,0.0004951544,0.0005422427],"domain_scores_gemma":[0.9986519,0.00004350939,0.0001512831,0.0006687962,0.00007107163,0.0004133967],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007368912,0.000134672,0.0002994209,0.00002602228,0.000146261,0.0001143349,0.0001693492,0.0002284008,0.9899422,0.0001733481,0.008669846,0.00002245393],"study_design_scores_gemma":[0.002404262,0.0003822043,0.0008430241,0.000134401,0.00005572284,0.000006876002,0.001784503,0.0001578324,0.9906119,0.000120695,0.003101885,0.0003967293],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.994015,0.001850646,0.0002446112,0.0005337872,0.0005137983,0.000668704,0.0003745821,0.0001445751,0.001654313],"genre_scores_gemma":[0.9931414,0.0002197758,0.0001203939,0.001022665,0.000327606,0.0003591916,0.004408161,0.00008187303,0.000318941],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005567961,"threshold_uncertainty_score":0.9998664,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00719283407494528,"score_gpt":0.2629926366905897,"score_spread":0.2557998026156444,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}