{"id":"W4319786746","doi":"10.3324/haematol.2022.281958","title":"Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis","year":2023,"lang":"en","type":"article","venue":"Haematologica","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Kite Pharma; Sanofi Genzyme; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; MorphoSys; Daiichi-Sankyo; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; TG Therapeutics; Medical College of Wisconsin; StemCyte; HistoGenetics; Karyopharm Therapeutics; CareDx; Actinium Pharmaceuticals; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Amgen; Accenture; Sanofi; GlaxoSmithKline; CSL Behring; Bristol-Myers Squibb; Astellas Pharma US; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Medac; Jazz Pharmaceuticals; Seagen; Be The Match Foundation","keywords":"Busulfan; Fludarabine; Medicine; Hazard ratio; Internal medicine; Melphalan; Cyclophosphamide; Myelofibrosis; Transplantation; Gastroenterology; Regimen; Surgery; Hematopoietic stem cell transplantation; Hematopoietic cell; Proportional hazards model; Oncology; Chemotherapy; Confidence interval; Bone marrow; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009070258,0.0001444024,0.0002054253,0.0002225738,0.0001768601,0.000391593,0.0002402515,0.0003113107,0.001369269],"category_scores_gemma":[0.00268465,0.0001041251,0.000414038,0.0003804187,0.0002035275,0.0002232347,0.0002956207,0.0007556973,0.0001039158],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000338588,"about_ca_system_score_gemma":0.0003436586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002097602,"about_ca_topic_score_gemma":0.00378138,"domain_scores_codex":[0.999607,0.0001174925,0.00004850962,0.0000708353,0.0000730711,0.00008312233],"domain_scores_gemma":[0.9983733,0.0004301944,0.000779454,0.0000840236,0.00009731786,0.000235701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009168481,0.00006341888,0.9947473,0.00002454236,0.0001380921,0.00007970015,0.00002318146,0.0001826438,0.0002925847,0.00004824681,0.0001979761,0.003285375],"study_design_scores_gemma":[0.00003768586,0.0002209732,0.9982527,0.00003284236,0.0001312999,0.0002202405,0.00007104105,0.0005124415,0.0001296766,0.00009078623,0.0002948993,0.000005402841],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9981074,0.00103885,0.00005866501,0.0001056251,0.00001274355,0.000005310103,0.0001661597,0.000001966094,0.0005032381],"genre_scores_gemma":[0.9994799,0.0002007184,0.0000286577,0.00003521537,0.00001752641,0.000003738801,0.0001563987,0.000001211475,0.00007663051],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002097602,"threshold_uncertainty_score":0.004796803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03062084220648969,"score_gpt":0.2970089551485368,"score_spread":0.2663881129420471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}