{"id":"W4319786746","doi":"10.3324/haematol.2022.281958","title":"Association between the choice of the conditioning regimen and outcomes of allogeneic hematopoietic cell transplantation for myelofibrosis","year":2023,"lang":"en","type":"article","venue":"Haematologica","topic":"Myeloproliferative Neoplasms: Diagnosis and Treatment","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"National Institute of Allergy and Infectious Diseases; Office of Naval Research; Legend Biotech; Pharmacyclics; Kite Pharma; Sanofi Genzyme; Takeda Oncology; Health Resources and Services Administration; National Institutes of Health; MorphoSys; Daiichi-Sankyo; Omeros Corporation; Astellas Pharma; Adaptive Biotechnologies; Pfizer; Incyte; Kiadis Pharma; bluebird bio; TG Therapeutics; Medical College of Wisconsin; StemCyte; HistoGenetics; Karyopharm Therapeutics; CareDx; Actinium Pharmaceuticals; Daiichi Sankyo Europe; National Cancer Institute; Gilead Sciences; Amgen; Accenture; Sanofi; GlaxoSmithKline; CSL Behring; Bristol-Myers Squibb; Astellas Pharma US; National Heart, Lung, and Blood Institute; Novartis Pharmaceuticals Corporation; Medac; Jazz Pharmaceuticals; Seagen; Be The Match Foundation","keywords":"Busulfan; Fludarabine; Medicine; Hazard ratio; Internal medicine; Melphalan; Cyclophosphamide; Myelofibrosis; Transplantation; Gastroenterology; Regimen; Surgery; Hematopoietic stem cell transplantation; Hematopoietic cell; Proportional hazards model; Oncology; Chemotherapy; Confidence interval; Bone marrow; Haematopoiesis; Stem cell","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002115946,0.00009184289,0.0003565597,0.00003330926,0.0001272864,0.000006580199,0.00005648353,0.00007487294,0.00001988726],"category_scores_gemma":[0.0001712113,0.0000454054,0.0001074887,0.0001372324,0.00005485114,0.00002271807,0.00001666508,0.00004796756,0.000004135651],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002094217,"about_ca_system_score_gemma":0.00002052103,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001640043,"about_ca_topic_score_gemma":0.00000892269,"domain_scores_codex":[0.9992378,0.00006884857,0.0002626456,0.0001310748,0.0001778702,0.0001217388],"domain_scores_gemma":[0.9979404,0.001557717,0.000263468,0.000135596,0.0000793884,0.00002346505],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00001774409,0.00004081173,0.9969261,0.0002904655,0.0001929517,0.000001170106,0.0005334293,0.000006659056,0.0006941223,0.0005896103,0.0005924383,0.0001144764],"study_design_scores_gemma":[0.0008168264,0.0001354111,0.9296177,0.00007878923,0.0005136892,0.0000042718,0.0001448396,0.00001280681,0.06802641,0.0004826654,0.000125158,0.00004143575],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935468,0.0001065116,0.00004287798,0.0051428,0.00003255441,0.0007611206,0.00008754489,0.00002166281,0.0002580993],"genre_scores_gemma":[0.9990121,0.0001482952,0.0002238055,0.0001120669,0.00001236496,0.0001753129,0.00005961344,0.000007201177,0.0002492439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06733228,"threshold_uncertainty_score":0.1851578,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03062084220648969,"score_gpt":0.2970089551485368,"score_spread":0.2663881129420471,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}