{"id":"W4319815466","doi":"10.1021/acs.bioconjchem.2c00569","title":"Ion-Pair-Enhanced Double-Click Driven Cell Adhesion and Altered Expression of Related Genes","year":2023,"lang":"en","type":"article","venue":"Bioconjugate Chemistry","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Japan Science and Technology Agency; Japan Society for the Promotion of Science; Tokuyama Science Foundation; Inamori Foundation; Japan Agency for Medical Research and Development; Asahi Glass Foundation","keywords":"Chemistry; Azide; Cationic polymerization; Substrate (aquarium); Cell; Biophysics; Cell adhesion; Adhesion; Kinetics; Click chemistry; Polymer chemistry; Biochemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002167023,0.0004659485,0.0002290693,0.0001090129,0.00009241443,0.0002417527,0.0002169259,0.0003364407,0.0008124146],"category_scores_gemma":[0.000175157,0.0001449084,0.0002484278,0.0001432364,0.0002783389,0.0002315961,0.0002732482,0.0004192425,0.0001938206],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003379027,"about_ca_system_score_gemma":0.0001732406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003369091,"about_ca_topic_score_gemma":0.0005971395,"domain_scores_codex":[0.9998241,0.00002091424,0.0000131125,0.00005053869,0.000048858,0.0000425365],"domain_scores_gemma":[0.9998724,0.00003508165,0.00004431975,0.00001306267,0.00001366006,0.00002134111],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001649222,0.000005770975,0.00003664086,0.00001248194,0.000001703857,0.00002960602,0.000006353263,0.0000317028,0.9994227,0.00007042741,0.00001214989,0.0003541282],"study_design_scores_gemma":[0.000003032312,0.00003358736,0.0002965661,4.132946e-7,0.000001890264,0.00005798041,0.000002482944,0.0002479716,0.9990194,0.000006510225,0.0003283683,0.000001837236],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9866106,0.0004196405,0.01141497,0.00006635991,0.00003148925,0.00004826023,0.0001193466,0.00006923015,0.001220124],"genre_scores_gemma":[0.9896458,0.0003456245,0.006773144,0.00004370185,0.000005622953,0.00005130083,0.0001976039,0.00002683096,0.002910378],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008124146,"threshold_uncertainty_score":0.002717793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01351347699150515,"score_gpt":0.2413129451132602,"score_spread":0.227799468121755,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}