{"id":"W4319826848","doi":"10.1111/exd.14760","title":"Does immune dysregulation contribute towards development of hypopigmentation in Indian post kala‐azar dermal leishmaniasis?","year":2023,"lang":"en","type":"article","venue":"Experimental Dermatology","topic":"Research on Leishmaniasis Studies","field":"Medicine","cited_by":4,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Indian Council of Medical Research; Department of Health Research, India; Mount Royal University","keywords":"Hypopigmentation; Microphthalmia-associated transcription factor; CXCL10; Chemokine; CD8; CXCL9; Immune system; Immunology; FOXP3; Medicine; Biology; Tyrosinase; Dermatology","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000242155,0.0002316862,0.0006200296,0.0006151545,0.000143633,0.00001700745,0.0001469157,0.000149707,0.0001467097],"category_scores_gemma":[0.0001214922,0.0001782394,0.00009360121,0.0005279735,0.000203666,0.0002132552,0.0002307177,0.0001760394,0.0001450449],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003247206,"about_ca_system_score_gemma":0.0002241821,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001416959,"about_ca_topic_score_gemma":0.0001337958,"domain_scores_codex":[0.9976411,0.0001424913,0.0008197472,0.0003574464,0.0004825668,0.0005566354],"domain_scores_gemma":[0.9992356,0.00008389576,0.0001733853,0.000247537,0.0001448618,0.0001147549],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008170893,0.0008161218,0.1735772,0.0003775737,0.0003868069,0.0009816446,0.02479999,0.000009546637,0.78692,0.0005616835,0.0008459598,0.009906447],"study_design_scores_gemma":[0.002133423,0.0000862275,0.4522645,0.00006380602,0.000008278967,0.0001063422,0.006132456,0.0000686948,0.5386024,0.00002195908,0.0003951794,0.0001168304],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942963,0.0006233234,0.00002443696,0.003353793,0.000293264,0.0008049135,0.00001486806,0.000106383,0.0004827912],"genre_scores_gemma":[0.9980134,0.00006439636,0.0009265137,0.0001666431,0.00003611269,0.000226958,0.0003814819,0.0000308593,0.0001536384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2786873,"threshold_uncertainty_score":0.7268392,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02122909985122851,"score_gpt":0.3245805832881071,"score_spread":0.3033514834368786,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}