{"id":"W4319881249","doi":"10.1159/000529311","title":"Macrocytosis in Mitochondrial DNA Deletion Syndromes","year":2023,"lang":"en","type":"article","venue":"Acta Haematologica","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Vancouver General Hospital; University of British Columbia","funders":"","keywords":"Macrocytosis; Heteroplasmy; Chronic progressive external ophthalmoplegia; Mitochondrial DNA; Mitochondrial encephalomyopathy; Kearns–Sayre syndrome; Lactic acidosis; Mitochondrial disease; Mitochondrial myopathy; Medicine; Genetics; Pathology; Internal medicine; Biology; Anemia","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002077856,0.0004551272,0.000321481,0.001037375,0.0003825311,0.0003149081,0.0003272943,0.0003893525,0.00161228],"category_scores_gemma":[0.001286127,0.0001408005,0.0001464457,0.0007282055,0.0003792488,0.0002344311,0.0005204577,0.0002983288,0.0004029665],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001928131,"about_ca_system_score_gemma":0.0002051389,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001923896,"about_ca_topic_score_gemma":0.003335428,"domain_scores_codex":[0.999779,0.00003319947,0.00003624974,0.0000483527,0.00005311842,0.00005002058],"domain_scores_gemma":[0.9995512,0.0001223492,0.0001516151,0.00002404511,0.00007458484,0.00007624589],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"observational","study_design_scores_codex":[0.0002996295,0.00003859499,0.3592986,0.0004245457,0.00007155916,0.5545338,0.001094318,0.0003555306,0.02438971,0.001212942,0.003805805,0.05447501],"study_design_scores_gemma":[0.00001206834,0.00007232314,0.1777221,0.0001265479,0.00005097087,0.8098496,0.0002861453,0.0002706337,0.002190378,0.0006718752,0.008735091,0.00001223996],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9515773,0.02474445,0.00394248,0.0007370834,0.0001808166,0.0001246247,0.0006658356,0.0002238335,0.01780356],"genre_scores_gemma":[0.9926991,0.004335194,0.001018136,0.0003243259,0.0001604247,0.0000166847,0.0002533858,0.0000185783,0.001174138],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001923896,"threshold_uncertainty_score":0.005393624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02462344037200738,"score_gpt":0.2686418050922986,"score_spread":0.2440183647202913,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}