{"id":"W4319965089","doi":"10.1099/acmi.0.000572.v1.3","title":"Reviewer response for version 1","year":2023,"lang":"en","type":"peer-review","venue":"","topic":"Microbial Natural Products and Biosynthesis","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"","keywords":"Virulence; Escherichia coli; Microbiology; Biology; Fermentation; Heterologous; Secondary metabolite; Secretion; Yeast extract; Mode of action; Bioassay; Gene cluster; Streptomyces coelicolor; Gene; Biochemistry; Mutant; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.01807341,0.001613569,0.002513513,0.00457654,0.003340623,0.009783317,0.004621573,0.008416734,0.6423535],"category_scores_gemma":[0.2041736,0.001013314,0.00283802,0.003199474,0.001548704,0.0074406,0.005800723,0.008500189,0.3148427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00444396,"about_ca_system_score_gemma":0.009434191,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003083412,"about_ca_topic_score_gemma":0.004455087,"domain_scores_codex":[0.9875398,0.003956728,0.001795719,0.001407686,0.004097542,0.001202622],"domain_scores_gemma":[0.8458608,0.02360649,0.004346828,0.006737675,0.110918,0.008530202],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00002008458,0.000002507649,0.00001713138,0.0002252944,0.00000276097,0.000009262905,0.00001623766,0.000004192271,0.000006767038,0.0001428188,0.9962221,0.003330856],"study_design_scores_gemma":[0.00008622521,0.00001796492,0.0003030965,0.001241758,0.00001246152,0.00005303884,0.0001597625,0.00002649309,0.00005047221,0.0007256889,0.9972954,0.00002753832],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"editorial","genre_gemma":"other","genre_scores_codex":[0.0002444586,0.002122259,0.001405074,0.2818453,0.6471192,0.001718242,0.01991171,0.002767161,0.0428666],"genre_scores_gemma":[0.007169943,0.005410875,0.005349672,0.3520969,0.1494994,0.01072356,0.02090565,0.006539162,0.4423048],"genre_candidate":"other","genre_consensus":null,"teacher_disagreement_score":0.3576465,"threshold_uncertainty_score":0.5101393,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05361506526202518,"score_gpt":0.3426403942274467,"score_spread":0.2890253289654215,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}