{"id":"W4319965894","doi":"10.1016/j.ehb.2023.101233","title":"Differential methylation in CD44 and SEC23A is associated with time preference in older individuals","year":2023,"lang":"en","type":"article","venue":"Economics & Human Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Health and Social Care Research and Development Division; Economic and Social Research Council; Office of the First Minister and Deputy First Minister; Queen's University; National Institutes of Health; Science Foundation Ireland; Department for the Economy; Centre for Ageing Research and Development in Ireland; United Kingdom Clinical Research Collaboration; Wellcome Trust; Queen's University Belfast; Public Health Agency; Medical Research Council; Atlantic Philanthropies","keywords":"DNA methylation; Preference; CpG site; Epigenetics; Cohort; Methylation; Trait; Population; Demography; Psychology; Genetics; Medicine; Biology; Bioinformatics; Internal medicine; Gene; Statistics; Computer science; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002507283,0.0001264771,0.0001926292,0.0001548079,0.00004068945,0.00001938462,0.00009086013,0.0002410867,0.00006163094],"category_scores_gemma":[0.00003208521,0.0001253387,0.00002148819,0.00008731324,0.00005639286,0.000004991761,0.00009240017,0.00008806923,0.00001173512],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002308687,"about_ca_system_score_gemma":0.00002649683,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003225821,"about_ca_topic_score_gemma":0.0006419639,"domain_scores_codex":[0.9990538,0.00009910909,0.0002442483,0.0003636113,0.00002080476,0.0002184474],"domain_scores_gemma":[0.9996573,0.00003439499,0.0001076781,0.0001475215,0.00001881861,0.00003430462],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003040759,0.00006934146,0.6222613,0.000007200219,0.0000654774,0.000001144299,0.00044287,0.000209593,0.3741131,0.0004545499,0.00004461381,0.002300377],"study_design_scores_gemma":[0.001543884,0.0003329261,0.9165462,0.00001589226,0.00001046604,5.365343e-7,0.0000224251,0.000695284,0.07481839,0.005103805,0.0006286013,0.0002815654],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991475,0.0001312747,0.00007182431,0.00007065429,0.00003887393,0.0001763428,0.00004278525,0.00001015152,0.0003105497],"genre_scores_gemma":[0.998406,0.0002556596,0.00003194847,0.00004744169,0.00004573366,0.00002310344,0.0009352658,0.00001564403,0.0002391957],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2992947,"threshold_uncertainty_score":0.5111165,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148050004925175,"score_gpt":0.257808343912442,"score_spread":0.2363278438631902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}