{"id":"W4319965894","doi":"10.1016/j.ehb.2023.101233","title":"Differential methylation in CD44 and SEC23A is associated with time preference in older individuals","year":2023,"lang":"en","type":"article","venue":"Economics & Human Biology","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging; Health and Social Care Research and Development Division; Economic and Social Research Council; Office of the First Minister and Deputy First Minister; Queen's University; National Institutes of Health; Science Foundation Ireland; Department for the Economy; Centre for Ageing Research and Development in Ireland; United Kingdom Clinical Research Collaboration; Wellcome Trust; Queen's University Belfast; Public Health Agency; Medical Research Council; Atlantic Philanthropies","keywords":"DNA methylation; Preference; CpG site; Epigenetics; Cohort; Methylation; Trait; Population; Demography; Psychology; Genetics; Medicine; Biology; Bioinformatics; Internal medicine; Gene; Statistics; Computer science; Environmental health","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004145656,0.0001631892,0.0002003341,0.000330041,0.0002521814,0.0003257552,0.0001825368,0.0003100253,0.002478802],"category_scores_gemma":[0.001752734,0.0001258967,0.0003829851,0.000478083,0.0001691488,0.0001453925,0.0002193649,0.0003287801,0.0001681818],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001847005,"about_ca_system_score_gemma":0.0001246408,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.005543187,"about_ca_topic_score_gemma":0.006860516,"domain_scores_codex":[0.9998015,0.00005578276,0.00001642127,0.0000614803,0.00003057436,0.00003427286],"domain_scores_gemma":[0.9993895,0.0001259386,0.0002671295,0.0000806364,0.00005607034,0.00008061426],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0004825699,0.00003557191,0.989595,0.00001615361,0.0001314781,0.0001058568,0.0001861664,0.00009060685,0.003885758,0.00006842849,0.0001499304,0.005252489],"study_design_scores_gemma":[0.00000333152,0.00005375534,0.9991874,0.000002240075,0.00002088235,0.0001023958,0.00004937729,0.000164484,0.0002261079,0.00006371963,0.0001236837,0.000002600171],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993451,0.0001264915,0.0001379225,0.0000305403,0.000002173194,0.000002143875,0.0001579655,0.000002246089,0.0001954157],"genre_scores_gemma":[0.9993437,0.00004592797,0.0001145528,0.00001425493,0.000003130419,0.000003402357,0.0001044823,0.000001298775,0.0003691817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005543187,"threshold_uncertainty_score":0.01102179,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02148050004925175,"score_gpt":0.257808343912442,"score_spread":0.2363278438631902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}