{"id":"W4319966429","doi":"10.3390/biomedicines11020505","title":"Stem Cell Therapies in Movement Disorders: Lessons from Clinical Trials","year":2023,"lang":"en","type":"review","venue":"Biomedicines","topic":"Pluripotent Stem Cells Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":9,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen's University","funders":"","keywords":"Disease; Medicine; Clinical trial; Spinocerebellar ataxia; Movement disorders; Amyotrophic lateral sclerosis; Therapeutic approach; Huntington's disease; Bioinformatics; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.005391708,0.0009047867,0.002167345,0.001805286,0.0003616586,0.001918393,0.001551604,0.002559287,0.004227812],"category_scores_gemma":[0.00703834,0.0002956655,0.0011789,0.00174598,0.001176118,0.00275959,0.001154693,0.00401427,0.001325985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001333861,"about_ca_system_score_gemma":0.002687224,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001005262,"about_ca_topic_score_gemma":0.002113327,"domain_scores_codex":[0.9988747,0.0004230822,0.0001969826,0.000123274,0.0003190794,0.00006288766],"domain_scores_gemma":[0.9945293,0.004382947,0.0002413508,0.00009000619,0.0005706731,0.000185729],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"systematic_review","study_design_scores_codex":[0.0002073788,0.00008872716,0.0001097706,0.02953839,0.0001810825,0.0002110863,0.0001193235,0.0004163191,0.0006152569,0.01393944,0.03506963,0.9195037],"study_design_scores_gemma":[0.000179917,0.0002786781,0.0004628229,0.04554273,0.0003348264,0.0007119934,0.0001462121,0.0001406755,0.0003657619,0.01525076,0.9365573,0.00002831154],"study_design_candidate":"systematic_review","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00004874656,0.9981135,0.0001057317,0.0009753566,0.000226455,0.000006751482,0.00001216927,0.000004898116,0.0005063079],"genre_scores_gemma":[0.0006408049,0.9974965,0.0002975757,0.001084358,0.0002178957,0.00001956837,0.00001848432,0.000003012741,0.0002216965],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.005391708,"threshold_uncertainty_score":0.02851439,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2833875904547534,"score_gpt":0.5014122172364177,"score_spread":0.2180246267816643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}