{"id":"W4319973481","doi":"10.3390/cells12040560","title":"Harnessing Innate Immunity to Treat Mycobacterium tuberculosis Infections: Heat-Killed Caulobacter crescentus as a Novel Biotherapeutic","year":2023,"lang":"en","type":"article","venue":"Cells","topic":"Immune Cell Function and Interaction","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Mitacs; University of British Columbia; University of Alberta","funders":"Canadian Institutes of Health Research","keywords":"Mycobacterium tuberculosis; Innate immune system; Tuberculosis; Immunology; Immunity; Biology; Population; Immune system; Microbiology; Virology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00015994,0.000310953,0.0002525907,0.0002063467,0.00009039781,0.0002309209,0.0002455275,0.0002461418,0.0004033596],"category_scores_gemma":[0.00004866276,0.00006882658,0.0001582241,0.0001070595,0.0002983652,0.0001760129,0.0001466005,0.0005340867,0.0001006332],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001810124,"about_ca_system_score_gemma":0.0002254232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000519049,"about_ca_topic_score_gemma":0.001123415,"domain_scores_codex":[0.9999371,0.00001241174,0.000003023392,0.00001125535,0.00001602107,0.00002037762],"domain_scores_gemma":[0.9999731,0.000004098316,0.000006948187,0.0000045149,0.000003439107,0.000007912892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009810448,0.0000980292,0.0001043609,0.00007297608,0.000004055624,0.0000453786,0.00001416464,0.0001473873,0.9929008,0.0001989451,0.00006405228,0.006251683],"study_design_scores_gemma":[0.00007097849,0.001877291,0.001560033,0.00001614316,0.00002329521,0.0003484796,0.00001542325,0.0008390709,0.9898867,0.00008497023,0.005271762,0.000006016698],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9750372,0.01533078,0.00641962,0.0005484356,0.0001266344,0.0001224747,0.000133748,0.0001263017,0.0021548],"genre_scores_gemma":[0.9880372,0.005468848,0.00464606,0.0001610812,0.00003629946,0.0000518636,0.00009154133,0.000009094921,0.001498001],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000519049,"threshold_uncertainty_score":0.001349449,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01600238499471524,"score_gpt":0.2596953819927755,"score_spread":0.2436929969980603,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}