{"id":"W4320008451","doi":"10.14283/jpad.2023.17","title":"Cross-Sectional and Longitudinal Comparison of Tau Imaging with 18F-MK6240 and 18F-Flortaucipir in Populations Matched for Age, MMSE and Brain Beta-Amyloid Burden","year":2023,"lang":"en","type":"article","venue":"The Journal of Prevention of Alzheimer s Disease","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Prothena; Northern California Institute for Research and Education; Eli Lilly and Company; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Medical Research Council; Meso Scale Diagnostics; Australian Government; F. Hoffmann-La Roche; University of Southern California; Pfizer; BioClinica; Biogen; Cerveau Technologies; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Commonwealth Scientific and Industrial Research Organisation; Foundation for the National Institutes of Health","keywords":"Entorhinal cortex; Temporal lobe; Internal medicine; Alzheimer's disease; Psychology; Temporal cortex; Neuroimaging; Nuclear medicine; Medicine; Hippocampus; Neuroscience; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001830842,0.0003181639,0.0003089775,0.0006636762,0.000396284,0.0003939594,0.0002844496,0.0006753561,0.0008993877],"category_scores_gemma":[0.002572918,0.0002983516,0.0003759852,0.0002928665,0.0002960429,0.0004094359,0.0003110633,0.0003403625,0.0002642648],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002459541,"about_ca_system_score_gemma":0.0001392992,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001545307,"about_ca_topic_score_gemma":0.001380193,"domain_scores_codex":[0.9994468,0.0001568399,0.00003860449,0.000244598,0.00005265162,0.00006049747],"domain_scores_gemma":[0.998785,0.0002650511,0.0003941318,0.0002205629,0.000187923,0.0001474219],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01085687,0.0003694668,0.9690972,0.00004186431,0.0009226914,0.0002072941,0.0004370658,0.0001182842,0.01211379,0.0000777682,0.0001270206,0.005630672],"study_design_scores_gemma":[0.0001422254,0.002830855,0.9947104,0.00000591735,0.0002797308,0.0004010877,0.000152524,0.0002588328,0.0008831351,0.00005833552,0.0002710367,0.000005871872],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9993642,0.0002360648,0.0001839629,0.000005035871,0.000004823807,0.000009003785,0.00008752193,0.000003155512,0.0001062538],"genre_scores_gemma":[0.99943,0.00005996016,0.0001426659,0.000009135558,0.000006286069,0.00001748897,0.0002272438,0.00000229381,0.0001048781],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001830842,"threshold_uncertainty_score":0.009682536,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09211671414900034,"score_gpt":0.4225640090584364,"score_spread":0.330447294909436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}