{"id":"W4320008451","doi":"10.14283/jpad.2023.17","title":"Cross-Sectional and Longitudinal Comparison of Tau Imaging with 18F-MK6240 and 18F-Flortaucipir in Populations Matched for Age, MMSE and Brain Beta-Amyloid Burden","year":2023,"lang":"en","type":"article","venue":"The Journal of Prevention of Alzheimer s Disease","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Health and Medical Research Council; National Institutes of Health; Genentech; IXICO; H. Lundbeck A/S; Servier; Eisai; National Institute of Biomedical Imaging and Bioengineering; Canadian Institutes of Health Research; Prothena; Northern California Institute for Research and Education; Eli Lilly and Company; U.S. Department of Defense; Alzheimer's Disease Neuroimaging Initiative; Medical Research Council; Meso Scale Diagnostics; Australian Government; F. Hoffmann-La Roche; University of Southern California; Pfizer; BioClinica; Biogen; Cerveau Technologies; Novartis Pharmaceuticals Corporation; Bristol-Myers Squibb; National Institute on Aging; Commonwealth Scientific and Industrial Research Organisation; Foundation for the National Institutes of Health","keywords":"Entorhinal cortex; Temporal lobe; Internal medicine; Alzheimer's disease; Psychology; Temporal cortex; Neuroimaging; Nuclear medicine; Medicine; Hippocampus; Neuroscience; Disease","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001130353,0.0001015963,0.0002985046,0.0002718437,0.000091027,0.00003017569,0.00005549363,0.00001585357,0.00005750473],"category_scores_gemma":[0.00009318323,0.00007149078,0.00008401895,0.0001932724,0.000246069,0.0001922566,0.00005503968,0.0001305604,4.11871e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001095641,"about_ca_system_score_gemma":0.0000968419,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003602221,"about_ca_topic_score_gemma":0.00002221137,"domain_scores_codex":[0.9987118,0.0001155923,0.0005150561,0.0001237748,0.000381886,0.0001519449],"domain_scores_gemma":[0.9990208,0.0001395784,0.0003258471,0.00008370546,0.0002669391,0.0001631099],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001846215,0.0002144015,0.9925506,0.0001497065,0.0003806018,0.0000251112,0.000296525,0.00007827681,0.001714323,0.00006007934,0.0001283906,0.002555752],"study_design_scores_gemma":[0.003298,0.0004978366,0.9917676,0.0002196175,0.001014905,0.00005950098,0.0005359338,0.0009330034,0.0004021386,0.001187382,0.00002004735,0.00006404117],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9954497,0.002264886,0.0004427352,0.001268996,0.00002787853,0.0004857472,0.00002924936,0.000005178686,0.00002559466],"genre_scores_gemma":[0.9993444,0.00007030115,0.0003183604,0.00001965518,0.00005347577,0.0000112314,0.0000222638,0.00001163446,0.0001486609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003894682,"threshold_uncertainty_score":0.2915309,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09211671414900034,"score_gpt":0.4225640090584364,"score_spread":0.330447294909436,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}