{"id":"W4320075776","doi":"10.15173/sciential.vi8.3016","title":"The Potentiation of Cortical Pyramidal Neurons Due to the Gain of Function Mutation of Kv.4.2 Channels","year":2022,"lang":"en","type":"article","venue":"Sciential - McMaster Undergraduate Science Journal","topic":"Cardiac electrophysiology and arrhythmias","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Long-term potentiation; Neuroscience; AMPA receptor; Excitatory postsynaptic potential; Glutamatergic; Mutation; Biology; Chemistry; Inhibitory postsynaptic potential; NMDA receptor; Genetics; Receptor; Glutamate receptor; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001066675,0.0005375686,0.0002521125,0.0004748921,0.0002032168,0.0002546259,0.0002746929,0.0003387798,0.002466122],"category_scores_gemma":[0.000241599,0.0001544554,0.0003082428,0.000174514,0.0004550384,0.0001839473,0.0004121835,0.0005334167,0.0004078691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003628328,"about_ca_system_score_gemma":0.0002942078,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001601369,"about_ca_topic_score_gemma":0.003742557,"domain_scores_codex":[0.9998811,0.00001415846,0.00001213502,0.00002291186,0.00004257688,0.00002700033],"domain_scores_gemma":[0.999845,0.00002112295,0.00007049985,0.00001877807,0.0000157195,0.00002888618],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001248481,0.0000358424,0.001177798,0.00004592597,0.00001039808,0.001298991,0.00002779196,0.0001149793,0.9896559,0.0003488548,0.0002757793,0.006882911],"study_design_scores_gemma":[0.00007476885,0.001245163,0.1007451,0.00004249796,0.0000609404,0.01054652,0.0001268271,0.0009490656,0.8813521,0.0006415003,0.004182423,0.00003302915],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9890741,0.0009888924,0.002330903,0.000355602,0.00007824226,0.00005019356,0.0005315508,0.0002383162,0.006352212],"genre_scores_gemma":[0.9918977,0.001121976,0.001601238,0.0001465956,0.00001853617,0.00003930627,0.0001782763,0.0000372297,0.004958989],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002466122,"threshold_uncertainty_score":0.008249938,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01159226641923667,"score_gpt":0.2563527915508092,"score_spread":0.2447605251315725,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}