{"id":"W4320480698","doi":"10.1186/s13148-023-01435-7","title":"DNA methylation in peripheral blood leukocytes for the association with glucose metabolism and invasive breast cancer","year":2023,"lang":"en","type":"article","venue":"Clinical Epigenetics","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Institute of Nursing Research; University at Buffalo; MedStar Health Research Institute; Wake Forest University; University of Pittsburgh; Ohio State University; National Heart, Lung, and Blood Institute; Brigham and Women's Hospital; National Institutes of Health; U.S. Department of Health and Human Services","keywords":"Breast cancer; DNA methylation; Human genetics; Peripheral blood; Cancer; Medicine; Biology; Methylation; Bioinformatics; DNA; Oncology; Internal medicine; Physiology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003741108,0.0002238866,0.000257736,0.0005077389,0.0002946187,0.0003636967,0.0002504882,0.0003353297,0.003276231],"category_scores_gemma":[0.00127274,0.000117699,0.0004182573,0.0009754894,0.000142449,0.0001362856,0.0002186582,0.0004356243,0.0002249494],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001941843,"about_ca_system_score_gemma":0.0002867726,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002123581,"about_ca_topic_score_gemma":0.003361922,"domain_scores_codex":[0.9997322,0.00006454595,0.00001974429,0.0001102817,0.00003706442,0.00003616614],"domain_scores_gemma":[0.9994853,0.000164118,0.000175392,0.00005139391,0.00004051717,0.00008326326],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009686227,0.00004271649,0.9779657,0.00005446448,0.0004066473,0.0001211701,0.00004506832,0.0002485921,0.008853595,0.00005709201,0.0004882423,0.01074814],"study_design_scores_gemma":[0.00002177087,0.0001400124,0.9954593,0.00001165388,0.0002867528,0.0003080001,0.00003081965,0.0009983594,0.001832615,0.0001702373,0.0007353868,0.000005038661],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9942876,0.001262242,0.001397871,0.000151792,0.00002182802,0.00001899535,0.00208353,0.00005291307,0.000723306],"genre_scores_gemma":[0.9981399,0.0001057729,0.0007772926,0.00004893836,0.00001080247,0.0000190727,0.000576242,0.000008585939,0.000313384],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003276231,"threshold_uncertainty_score":0.0109601,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02763917136676283,"score_gpt":0.3288917756827276,"score_spread":0.3012526043159648,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}