{"id":"W4320482471","doi":"10.1038/s41419-023-05626-1","title":"Dynamic differentiation of F4/80+ tumor-associated macrophage and its role in tumor vascularization in a syngeneic mouse model of colorectal liver metastasis","year":2023,"lang":"en","type":"article","venue":"Cell Death and Disease","topic":"Immune cells in cancer","field":"Immunology and Microbiology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Science, Technology and Innovation Commission of Shenzhen Municipality; National Natural Science Foundation of China; Southern University of Science and Technology; York University","keywords":"Metastasis; Colorectal cancer; Cancer research; Macrophage; Biology; Pathology; Medicine; Cancer; In vitro; Genetics","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004349581,0.0007687778,0.0003295866,0.0009506317,0.0002380335,0.0003501879,0.0003308361,0.0006778958,0.001263596],"category_scores_gemma":[0.0001147023,0.0003041759,0.0003800508,0.0002310491,0.0004043471,0.0003381883,0.0002534406,0.001334071,0.000515289],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003799711,"about_ca_system_score_gemma":0.0002343189,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007770297,"about_ca_topic_score_gemma":0.0008306235,"domain_scores_codex":[0.9996536,0.00005604821,0.00003992564,0.00008730564,0.00006913364,0.00009408202],"domain_scores_gemma":[0.9996896,0.00002334056,0.00009204073,0.00004718907,0.0000294967,0.0001184093],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001878715,0.00008994868,0.0001150812,0.00002345449,0.000002209225,0.00004915688,0.00001729739,0.00005451632,0.9989015,0.0001060297,0.00002321212,0.0004296057],"study_design_scores_gemma":[0.00004246555,0.001242823,0.002436581,0.000009653268,0.00001756885,0.0003000235,0.00003756288,0.001281922,0.9927015,0.00007955801,0.001842221,0.00000820241],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907472,0.001062185,0.005895154,0.0001351172,0.00005765665,0.0001120012,0.0006426083,0.0001958537,0.001152261],"genre_scores_gemma":[0.9862557,0.0006716432,0.006234944,0.00007669174,0.00002347308,0.0002420952,0.0006446333,0.00006107667,0.005789637],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001263596,"threshold_uncertainty_score":0.004227102,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007676246151505199,"score_gpt":0.2083205402006711,"score_spread":0.2006442940491659,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}