{"id":"W4320486061","doi":"10.26508/lsa.202201810","title":"Dual function of Rab1A in secretion and autophagy: hypervariable domain dependence","year":2023,"lang":"en","type":"article","venue":"Life Science Alliance","topic":"Cellular transport and secretion","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Neurological Disorders and Stroke; National Institute of General Medical Sciences; National Institutes of Health; University of Alberta","keywords":"Autophagy; Rab; Cell biology; Secretion; GTPase; Endocytosis; Biology; Intracellular; Chemistry; Receptor; Apoptosis; Biochemistry","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002706019,0.000198123,0.0001903015,0.0002184648,0.000216471,0.0004743628,0.0001833414,0.0002492252,0.0007752628],"category_scores_gemma":[0.0002016615,0.0001196522,0.0002066328,0.0001670803,0.0002969092,0.000441279,0.0004238247,0.0003997981,0.0003519085],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003816707,"about_ca_system_score_gemma":0.0002584668,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003618038,"about_ca_topic_score_gemma":0.0003763915,"domain_scores_codex":[0.9998746,0.00002617958,0.000009841527,0.00002571235,0.00003578204,0.00002780539],"domain_scores_gemma":[0.9998834,0.00002681233,0.00002693794,0.00001908037,0.00001683567,0.00002690538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001696124,0.0000131451,0.001634691,0.00003880624,0.000009074527,0.0001196505,0.00001888902,0.0002116054,0.9903523,0.002154246,0.0000603405,0.00521762],"study_design_scores_gemma":[0.00003464159,0.0001836217,0.02689947,0.00001737426,0.00004101908,0.002658877,0.00007509513,0.006052719,0.9519278,0.002466321,0.009620256,0.00002286754],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.990011,0.00420938,0.003585043,0.0002690289,0.00001285084,0.000006747962,0.00008653214,0.00005762991,0.001761807],"genre_scores_gemma":[0.9973398,0.000832047,0.001010379,0.00005811713,0.000006126044,0.000005652615,0.0001346948,0.00001084139,0.000602251],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0007752628,"threshold_uncertainty_score":0.002769172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0121074781389548,"score_gpt":0.2346911542766626,"score_spread":0.2225836761377078,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}