{"id":"W4320495515","doi":"10.1101/2023.02.10.23285303","title":"Overestimation of anticoagulant benefit in patients with atrial fibrillation and low life expectancy: evidence from 12 randomized trials","year":2023,"lang":"en","type":"preprint","venue":"medRxiv","topic":"Atrial Fibrillation Management and Outcomes","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University; Population Health Research Institute","funders":"National Institute on Aging; University of California, San Francisco","keywords":"Atrial fibrillation; Life expectancy; Randomized controlled trial; Medicine; Internal medicine; Cardiology; Anticoagulant therapy; Population; Environmental health","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0628877,0.001649159,0.007137722,0.001698301,0.0004842129,0.003598569,0.001964803,0.004035356,0.003746118],"category_scores_gemma":[0.1528306,0.001180379,0.01859101,0.002175068,0.001933486,0.002343013,0.001408612,0.003288063,0.0004334577],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001659618,"about_ca_system_score_gemma":0.001800582,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001917132,"about_ca_topic_score_gemma":0.002237073,"domain_scores_codex":[0.9195498,0.0562101,0.01508223,0.004318852,0.004195232,0.0006437598],"domain_scores_gemma":[0.7427707,0.2105891,0.03266757,0.00659643,0.006483088,0.0008931068],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"meta_analysis","study_design_gemma":"meta_analysis","study_design_scores_codex":[0.1212717,0.0007403723,0.03310039,0.1579031,0.584518,0.0001890636,0.0003461341,0.00250006,0.0006164546,0.001218549,0.002124465,0.09547174],"study_design_scores_gemma":[0.1236836,0.01167869,0.04603086,0.06046252,0.7370467,0.0005103141,0.0002689991,0.00353936,0.001105747,0.00576341,0.00968653,0.0002234405],"study_design_candidate":"meta_analysis","study_design_consensus":"meta_analysis","genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.1312152,0.8453063,0.008826224,0.004631406,0.001540681,0.002849774,0.002046777,0.0001301666,0.003453454],"genre_scores_gemma":[0.8537514,0.1272278,0.007719464,0.004990727,0.001053111,0.003242883,0.001362041,0.00006903491,0.0005835399],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.0628877,"threshold_uncertainty_score":0.3325859,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1248432985273459,"score_gpt":0.3518454913926195,"score_spread":0.2270021928652736,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}