{"id":"W4320506938","doi":"","title":"MiR-181a-5p inhibits uveal melanoma development by targeting GNAQ and AKT3.","year":2023,"lang":"en","type":"article","venue":"PubMed","topic":"interferon and immune responses","field":"Immunology and Microbiology","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre Hospitalier de l’Université de Montréal; Université Laval; Centre hospitalier de l'Université Laval; Centre Hospitalier Universitaire Sainte-Justine; Université de Montréal","funders":"Fonds de Recherche du Québec - Santé; Canadian Institutes of Health Research; Université de Montréal","keywords":"GNAQ; AKT3; Cancer research; microRNA; Melanoma; Gene silencing; Cell growth; PI3K/AKT/mTOR pathway; Phosphorylation; Apoptosis; AKT1; Protein kinase B; Biology; Medicine; Mutation; Cell biology; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002035234,0.0005339254,0.0003764622,0.0003475858,0.0002911376,0.0003320008,0.0002735451,0.0004440814,0.001234327],"category_scores_gemma":[0.000173778,0.0002329947,0.0005634723,0.0002145821,0.0003610794,0.0002468774,0.000233091,0.001040418,0.0004889442],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004546326,"about_ca_system_score_gemma":0.000521044,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006121478,"about_ca_topic_score_gemma":0.001076814,"domain_scores_codex":[0.9998199,0.00002845711,0.00002708228,0.00003049987,0.00005289447,0.00004114953],"domain_scores_gemma":[0.9999429,0.000008800455,0.00001924656,0.000006145643,0.000008856741,0.00001418345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0005749427,0.0002393923,0.0005110948,0.0002679091,0.00003972062,0.0001517841,0.00005142981,0.0002953592,0.986238,0.0004724914,0.0007208747,0.01043699],"study_design_scores_gemma":[0.0002381827,0.001659837,0.005117272,0.00002155419,0.0001072567,0.0008446584,0.00006273419,0.003002358,0.9743113,0.0002518528,0.01436656,0.00001637328],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9651672,0.01429223,0.008725114,0.000787749,0.0004878581,0.0002534429,0.001014529,0.0008540177,0.008417827],"genre_scores_gemma":[0.9879121,0.003620969,0.004473166,0.0003015466,0.00003386762,0.0001471706,0.000885222,0.00003962782,0.002586285],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001234327,"threshold_uncertainty_score":0.004129231,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433861645785632,"score_gpt":0.204523049515676,"score_spread":0.1901844330578197,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}