{"id":"W4320709875","doi":"10.1172/jci165654","title":"Molecular pathways that drive diabetic kidney disease","year":2023,"lang":"en","type":"review","venue":"Journal of Clinical Investigation","topic":"Chronic Kidney Disease and Diabetes","field":"Medicine","cited_by":315,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Nutrition, Metabolism and Diabetes","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institutes of Health","keywords":"Kidney; Albuminuria; Kidney disease; Endocrinology; Diabetes mellitus; Podocyte; Internal medicine; Oxidative stress; Renal function; Diabetic nephropathy; Fibrosis; Medicine; Biology; Actin cytoskeleton; Proteinuria; Cell; Cytoskeleton; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004575571,0.0008211644,0.001061576,0.00153828,0.0002932649,0.001040664,0.000840643,0.0009156334,0.003446022],"category_scores_gemma":[0.0004994717,0.0002069256,0.0005069666,0.00128235,0.0004145393,0.001045556,0.0007137709,0.002106443,0.001982783],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006612829,"about_ca_system_score_gemma":0.001037198,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007306423,"about_ca_topic_score_gemma":0.001478344,"domain_scores_codex":[0.9998497,0.00002535089,0.00002061831,0.00002487716,0.00005582153,0.00002365121],"domain_scores_gemma":[0.9998358,0.00004674584,0.00002638152,0.000006060837,0.00006020572,0.00002476386],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001327748,0.0001136275,0.000398704,0.01518971,0.0001629039,0.0002899739,0.00005937723,0.0004243465,0.002613823,0.007954574,0.05182349,0.9208366],"study_design_scores_gemma":[0.00003139713,0.0001063134,0.001338421,0.004300462,0.0001306972,0.001420621,0.00005572543,0.0001341761,0.0007479624,0.005012805,0.9867012,0.00002015606],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001637795,0.9977302,0.0001362556,0.0005518287,0.00029621,0.000006166291,0.00002625347,0.0000131856,0.001076192],"genre_scores_gemma":[0.0007331308,0.9982664,0.0001244445,0.0002470685,0.0001364032,0.00000694508,0.00003448419,0.000001038711,0.0004501281],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003446022,"threshold_uncertainty_score":0.01152807,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1921302012424787,"score_gpt":0.4263697159941644,"score_spread":0.2342395147516857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}