{"id":"W4320916531","doi":"10.1503/cjs.017021","title":"Relation between mismatch repair status, chemoresponse, survival and anatomic location in gastroesophageal adenocarcinoma","year":2023,"lang":"en","type":"article","venue":"Canadian Journal of Surgery","topic":"Genetic factors in colorectal cancer","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University Health Centre; Montreal General Hospital","funders":"McGill University Health Centre; McGill University","keywords":"Medicine; MSH6; MSH2; Microsatellite instability; Internal medicine; Oncology; MLH1; Esophagectomy; Hazard ratio; PMS2; Adenocarcinoma; Lynch syndrome; Cancer; Gastroenterology; DNA mismatch repair; Esophageal cancer; Confidence interval; Colorectal cancer","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":true,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002752644,0.0001463664,0.000164825,0.0004813243,0.0002675828,0.0002193462,0.0002397134,0.0001663491,0.001098359],"category_scores_gemma":[0.0008553495,0.00008417886,0.0001977912,0.0006319992,0.0002826252,0.0001195969,0.0002331279,0.0001627882,0.0001016334],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008106689,"about_ca_system_score_gemma":0.0006624657,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.04263267,"about_ca_topic_score_gemma":0.07961737,"domain_scores_codex":[0.9998775,0.00001624955,0.00001041025,0.00002554424,0.00003881989,0.00003151031],"domain_scores_gemma":[0.9994635,0.00008758991,0.0002194432,0.0000255067,0.00009339204,0.0001105073],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00009516149,0.000005052858,0.9983089,0.000005592407,0.00001349752,0.0000487448,0.00001610299,0.00005848271,0.0005411363,0.000003026032,0.00001814608,0.0008862328],"study_design_scores_gemma":[0.000001964622,0.00004776181,0.9993092,0.000001689,0.00001258377,0.000270613,0.00003900481,0.0001014968,0.0001309563,0.000004947615,0.00007875551,0.000001207423],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9994538,0.0002272518,0.00002841546,0.00001502424,8.655747e-7,0.000002882216,0.0001232839,0.000001403685,0.0001471995],"genre_scores_gemma":[0.999711,0.00006698146,0.00004180718,0.000005068151,0.000001818584,0.000001343344,0.0001254049,5.310365e-7,0.00004612336],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.04263267,"threshold_uncertainty_score":0.08476901,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04604743211239565,"score_gpt":0.271378333757794,"score_spread":0.2253309016453983,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}