{"id":"W4320917309","doi":"10.3390/curroncol30020179","title":"Relapsed/Refractory Multiple Myeloma: A Review of Available Therapies and Clinical Scenarios Encountered in Myeloma Relapse","year":2023,"lang":"en","type":"review","venue":"Current Oncology","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":87,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute on Aging","keywords":"Medicine; Multiple myeloma; Chimeric antigen receptor; Lenalidomide; Disease; Oncology; Autologous stem-cell transplantation; Daratumumab; Intensive care medicine; Immunology; Internal medicine; Bioinformatics; Immunotherapy; Cancer","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005775702,0.000686106,0.001357678,0.00344338,0.0003023037,0.001026974,0.0007202571,0.001019499,0.003295968],"category_scores_gemma":[0.001480424,0.0003117402,0.000946686,0.003821839,0.0003286604,0.001238602,0.0005387864,0.00122848,0.000784451],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006717617,"about_ca_system_score_gemma":0.001436255,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001801078,"about_ca_topic_score_gemma":0.003449697,"domain_scores_codex":[0.9996897,0.00006416099,0.00008902758,0.00004638873,0.00008895527,0.00002181765],"domain_scores_gemma":[0.9992705,0.0004592647,0.0001275619,0.00001187439,0.000103359,0.00002744107],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001084337,0.00006570591,0.0002601873,0.09845931,0.0002465077,0.0003558078,0.0001746081,0.0004270507,0.0007434652,0.002381811,0.03391571,0.8628615],"study_design_scores_gemma":[0.0000273019,0.0001794628,0.001750228,0.05491741,0.0007858063,0.003253884,0.0002034112,0.0001480616,0.0002745654,0.001821656,0.9366062,0.00003189518],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.00007370661,0.9992384,0.00003551674,0.0001776647,0.00009677395,0.000003665194,0.00001694953,0.000002939006,0.0003543803],"genre_scores_gemma":[0.0003953983,0.9990962,0.00009984949,0.0001527606,0.00009446845,0.000004672237,0.00002106128,7.577553e-7,0.00013489],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00344338,"threshold_uncertainty_score":0.01102608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.3083256481737203,"score_gpt":0.4919326816277987,"score_spread":0.1836070334540784,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}