{"id":"W4321003708","doi":"10.1371/journal.pone.0281917","title":"Octopamine and tyramine signalling in Aedes aegypti: Molecular characterization and insight into potential physiological roles","year":2023,"lang":"en","type":"article","venue":"PLoS ONE","topic":"Neurobiology and Insect Physiology Research","field":"Neuroscience","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; University of Toronto Mississauga; University of Toronto","keywords":"Biology; Receptor; Aedes aegypti; Octopamine (neurotransmitter); G protein-coupled receptor; Malpighian tubule system; Neurohormones; Autacoid; Cell biology; Internal medicine; Endocrinology; Biochemistry; Serotonin; Midgut; Ecology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006405634,0.000270343,0.000259548,0.0003363494,0.0001333571,0.0002592388,0.000108767,0.0002561529,0.0007641379],"category_scores_gemma":[0.0000721801,0.0001061863,0.0005071317,0.0002968622,0.0001032316,0.0002129511,0.0001330771,0.0002937011,0.000361205],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000244122,"about_ca_system_score_gemma":0.0001546025,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002204742,"about_ca_topic_score_gemma":0.002894947,"domain_scores_codex":[0.9999652,0.000003036677,0.00000311482,0.00001247063,0.000009357388,0.000006941695],"domain_scores_gemma":[0.9999684,0.000004083682,0.00001248601,0.000001739585,0.0000050843,0.00000806783],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000201513,0.00001666655,0.00853394,0.0002493653,0.00004542735,0.0002573949,0.00004878815,0.0005186891,0.9821139,0.000181192,0.0002406788,0.007592427],"study_design_scores_gemma":[0.00009708152,0.000730919,0.5803005,0.0001332922,0.0006109087,0.003784077,0.0005900603,0.02901092,0.3415588,0.0008993052,0.04219632,0.00008778836],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9769297,0.009820043,0.005026707,0.0002709847,0.00002893797,0.00003555346,0.005746022,0.0001044669,0.002037666],"genre_scores_gemma":[0.9586776,0.01033476,0.01381524,0.0003652663,0.00002821984,0.00004134742,0.01393794,0.00003841615,0.002761202],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002204742,"threshold_uncertainty_score":0.004383743,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05441520530720432,"score_gpt":0.2633552127127778,"score_spread":0.2089400074055735,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}