{"id":"W4321004556","doi":"10.1001/jamanetworkopen.2022.55631","title":"Bidirectional Associations Between Adiposity and Cognitive Function and Mediation by Brain Morphology in the ABCD Study","year":2023,"lang":"en","type":"article","venue":"JAMA Network Open","topic":"Dementia and Cognitive Impairment Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"Simon Fraser University; University of Waterloo","funders":"","keywords":"Mediation; Brain morphometry; Cognition; Psychology; Brain function; Morphology (biology); Developmental psychology; Neuroscience; Medicine; Biology; Sociology; Magnetic resonance imaging","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002714408,0.00007768373,0.0001705582,0.00008385903,0.0002255765,0.0001220581,0.00007012476,0.00006804666,0.00006335502],"category_scores_gemma":[0.0003454637,0.00006043165,0.00001503337,0.0005815176,0.00004919305,0.0001700406,0.0001515171,0.0002375231,0.00002349321],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002660861,"about_ca_system_score_gemma":0.00003926126,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002672686,"about_ca_topic_score_gemma":0.0002129612,"domain_scores_codex":[0.9985424,0.0005725974,0.0001652403,0.000231735,0.0002731469,0.0002148733],"domain_scores_gemma":[0.9985713,0.001164155,0.00005832749,0.00006338509,0.00008508577,0.00005771544],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0001611951,0.0001429259,0.9610385,0.00000340953,0.0001770233,0.00001074479,0.0004287473,6.780378e-7,0.00003596216,0.00002419723,0.02459213,0.01338445],"study_design_scores_gemma":[0.002990522,0.000691222,0.9936556,0.00002133617,0.0001529924,0.000003761369,0.001198434,0.00009071796,0.000005327546,0.0005885222,0.0005430684,0.00005845335],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.987674,0.0001268748,0.00006162607,0.008779738,0.00005256404,0.001599951,0.00004720683,0.00002137494,0.001636678],"genre_scores_gemma":[0.9970844,0.00004587007,0.000007482022,0.001038539,0.0002638639,0.0002034893,0.0006549523,0.000007687866,0.0006937141],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03261711,"threshold_uncertainty_score":0.2464331,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03432218827336013,"score_gpt":0.3536135650684721,"score_spread":0.3192913767951119,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}