{"id":"W4321183784","doi":"10.2337/dc22-1385","title":"Gastrointestinal Consequences of Type 2 Diabetes Mellitus and Impaired Glycemic Homeostasis: A Mendelian Randomization Study","year":2023,"lang":"en","type":"article","venue":"Diabetes Care","topic":"Genetic Associations and Epidemiology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":155,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre for Global Health Research","funders":"Vetenskapsrådet; Hjärt-Lungfonden; Cancerfonden; Key Project of Research and Development Plan of Hunan Province; Science Fund for Distinguished Young Scholars of Zhejiang Province; National Natural Science Foundation of China; Forskningsrådet om Hälsa, Arbetsliv och Välfärd; British Heart Foundation; Wellcome Trust","keywords":"Medicine; Mendelian randomization; Diabetes mellitus; Glycemic; Internal medicine; Type 2 diabetes; Type 2 Diabetes Mellitus; Endocrinology; Genetics; Gene; Genetic variants; Biology; Genotype","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000256875,0.0001247584,0.0002569421,0.00007444877,0.00006866304,0.0000110436,0.00009362676,0.00005478838,0.000006835849],"category_scores_gemma":[0.0004865399,0.0001137435,0.00005206671,0.0002160235,0.0001154632,0.000002823354,0.00007741129,0.00004343727,0.000009205926],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009910144,"about_ca_system_score_gemma":0.00006251394,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001307279,"about_ca_topic_score_gemma":0.00001985825,"domain_scores_codex":[0.998987,0.0001593572,0.000250285,0.0002594669,0.00008111198,0.000262748],"domain_scores_gemma":[0.9993788,0.0000720885,0.0001226288,0.0001770297,0.0001931903,0.00005626887],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00007019601,0.00002352932,0.926339,0.00003617521,0.00007111757,9.017886e-7,0.000255662,0.0001730425,0.07064514,0.000003172144,0.0004156516,0.001966458],"study_design_scores_gemma":[0.007627787,0.005566588,0.9191437,0.0001207414,0.0002595409,0.000005027092,0.01933499,0.001304588,0.04501906,0.0003954362,0.0006433586,0.0005792212],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9970362,0.00237546,0.00001072972,0.00008472553,0.00007659943,0.0002776098,0.00007333117,0.00002258487,0.0000427956],"genre_scores_gemma":[0.9988207,0.0003042205,0.000338004,0.0000477127,0.00004260963,0.0000382571,0.0003801218,0.00001331108,0.00001502753],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02562607,"threshold_uncertainty_score":0.4638327,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01307854598525756,"score_gpt":0.2568436771651811,"score_spread":0.2437651311799236,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}