{"id":"W4321189307","doi":"10.1016/j.cellsig.2023.110631","title":"Parkin and mitochondrial signalling","year":2023,"lang":"en","type":"review","venue":"Cellular Signalling","topic":"Autophagy in Disease and Therapy","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Gips-Schüle-Stiftung","keywords":"Parkin; PINK1; Mitophagy; Cell biology; Ubiquitin ligase; Mitochondrion; Ubiquitin; MFN1; Biology; mitochondrial fusion; Phosphorylation; Chemistry; Biochemistry; Autophagy; Mitochondrial DNA; Parkinson's disease; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006438415,0.001294189,0.001891092,0.001723183,0.0003150011,0.001943142,0.0008492914,0.001451586,0.00578157],"category_scores_gemma":[0.0007565817,0.0003547602,0.0004291522,0.001800918,0.0007184716,0.001566826,0.001114458,0.003100237,0.003696894],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0008211894,"about_ca_system_score_gemma":0.001163952,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007737018,"about_ca_topic_score_gemma":0.002066513,"domain_scores_codex":[0.9998295,0.00003236209,0.0000225163,0.00003094528,0.0000604814,0.00002417617],"domain_scores_gemma":[0.9997837,0.00008913196,0.00004052745,0.000009003837,0.00004180735,0.00003583486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002855177,0.00009502983,0.00009341309,0.01398292,0.0001059393,0.0002009684,0.00004036962,0.0005837333,0.002289021,0.005833043,0.07381748,0.9026725],"study_design_scores_gemma":[0.00005910905,0.00007526467,0.0003287582,0.002823789,0.0001036498,0.0004575123,0.00003317745,0.0001187276,0.0002925598,0.003329422,0.9923632,0.0000148108],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0000591202,0.9977113,0.0001085638,0.0003733997,0.0004730464,0.000004687329,0.00002078612,0.000008872451,0.001240318],"genre_scores_gemma":[0.0006483389,0.9966159,0.0001544242,0.0004102798,0.0005946098,0.00000808643,0.00004892939,0.000002259169,0.001517215],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.00578157,"threshold_uncertainty_score":0.01934123,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07968382260189825,"score_gpt":0.3383634446303267,"score_spread":0.2586796220284284,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}