{"id":"W4321200492","doi":"10.1136/ard-2022-223751","title":"What is a response in randomised controlled trials in giant cell arteritis?","year":2023,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Vasculitis and related conditions","field":"Medicine","cited_by":11,"is_retracted":false,"has_abstract":false,"ca_institutions":"Mount Sinai Hospital; University Health Network","funders":"National Institutes of Health; Sanofi; European League Against Rheumatism; GlaxoSmithKline; American College of Rheumatology Research and Education Foundation; Pfizer; Eli Lilly and Company; Bristol-Myers Squibb; AstraZeneca","keywords":"Medicine; Giant cell arteritis; Adverse effect; Erythrocyte sedimentation rate; Disease; Randomized controlled trial; Gold standard (test); Intensive care medicine; Clinical endpoint; Physical therapy; Internal medicine; Vasculitis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":["metaresearch"],"consensus_categories":[],"category_scores_codex":[0.2480888,0.004698109,0.03025752,0.003412975,0.003323801,0.009884498,0.004264113,0.01940683,0.018797],"category_scores_gemma":[0.4456576,0.004230376,0.03526298,0.003811868,0.01110325,0.02004438,0.004656093,0.02710469,0.003163091],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.006206616,"about_ca_system_score_gemma":0.004513579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001913821,"about_ca_topic_score_gemma":0.002830797,"domain_scores_codex":[0.5385234,0.3540925,0.07158964,0.01321035,0.01692027,0.005663755],"domain_scores_gemma":[0.3997018,0.5358014,0.03433209,0.01250147,0.0117018,0.005961535],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"theoretical_or_conceptual","study_design_scores_codex":[0.4715425,0.001080771,0.006464554,0.2153639,0.1657698,0.0004677335,0.001321467,0.001606244,0.001454728,0.006951784,0.0286376,0.09933893],"study_design_scores_gemma":[0.7315656,0.0169653,0.015937,0.04633066,0.1055265,0.0005770697,0.000982509,0.002611012,0.001042343,0.03181401,0.04599415,0.0006539908],"study_design_candidate":"theoretical_or_conceptual","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.05414201,0.6834722,0.01737252,0.1384396,0.07613027,0.01323782,0.004050287,0.0008821245,0.01227324],"genre_scores_gemma":[0.6653531,0.08731143,0.02892962,0.1551302,0.03405154,0.02087247,0.003478311,0.0006516087,0.004221782],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.2480888,"threshold_uncertainty_score":0.9272403,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04912421236013309,"score_gpt":0.3383008583350646,"score_spread":0.2891766459749315,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}