{"id":"W4321350217","doi":"10.1016/j.ijpharm.2023.122740","title":"Therapeutic contact lenses for the treatment of corneal and ocular surface diseases: Advances in extended and targeted drug delivery","year":2023,"lang":"en","type":"review","venue":"International Journal of Pharmaceutics","topic":"Ocular Surface and Contact Lens","field":"Medicine","cited_by":34,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Waterloo","funders":"National Eye Institute; Research to Prevent Blindness","keywords":"Drug delivery; Medicine; Drug; Bioavailability; Contact lens; Pharmacology; Ophthalmology; Nanotechnology; Materials science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006519411,0.0008575476,0.001480225,0.002304088,0.0002166657,0.001211992,0.0007193715,0.000913264,0.003467188],"category_scores_gemma":[0.0006476547,0.0002328508,0.0007012569,0.002097064,0.0003945852,0.001232821,0.0006232265,0.001860485,0.001142477],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000450681,"about_ca_system_score_gemma":0.0008780616,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001109116,"about_ca_topic_score_gemma":0.00223953,"domain_scores_codex":[0.9997919,0.0000273597,0.00002480409,0.00003347708,0.0000977639,0.00002479023],"domain_scores_gemma":[0.9996318,0.0001939123,0.00005690658,0.00000968374,0.00008105104,0.00002663612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001021415,0.0001400397,0.0001462889,0.02007079,0.0001236992,0.0001601199,0.00005108026,0.0003864825,0.004626168,0.003303231,0.01121845,0.9596716],"study_design_scores_gemma":[0.00005391175,0.0003578515,0.001246904,0.004086095,0.0003477211,0.001475224,0.00007416839,0.0003312225,0.002619952,0.0017388,0.9876289,0.00003923974],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001686237,0.9989323,0.0001783092,0.00009956242,0.00009136779,0.000004795103,0.00001505176,0.000006100374,0.0005039771],"genre_scores_gemma":[0.0008470187,0.9984272,0.0002195493,0.0000881988,0.00006580741,0.000003987405,0.00001945508,9.856379e-7,0.0003278381],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003467188,"threshold_uncertainty_score":0.01159894,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06887471094686247,"score_gpt":0.4154593850992837,"score_spread":0.3465846741524212,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}