{"id":"W4321454185","doi":"10.1089/mdr.2022.0123","title":"Genetic and Phenotypic Characterization of the First Canadian Case of Ambler Class A Carbapenemase FRI-8","year":2023,"lang":"en","type":"article","venue":"Microbial Drug Resistance","topic":"Antibiotic Resistance in Bacteria","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ste. Anne's Hospital; Centre hospitalier de l'Université Laval; Public Health Agency of Canada","funders":"Public Health Agency; Public Health Agency of Canada","keywords":"Enterobacter cloacae; Carbapenem; Biology; Microbiology; Whole genome sequencing; Plasmid; DNA sequencing; Klebsiella pneumoniae; Enterobacter; Phenotype; Gene; Genetics; Genome; Computational biology; Escherichia coli; Antibiotics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001046166,0.0001283882,0.0001629626,0.00005423929,0.0001213967,0.00001476489,0.000186857,0.0000962751,0.00001201692],"category_scores_gemma":[0.00004353524,0.0001133441,0.00005872306,0.0002402525,0.0002026908,0.000003978413,0.00008592645,0.00005442302,0.000003149612],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002491689,"about_ca_system_score_gemma":0.0001692591,"about_ca_topic_candidate":true,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002810274,"about_ca_topic_score_gemma":0.1983422,"domain_scores_codex":[0.9991242,0.00005060505,0.0002666216,0.0002652371,0.00006620496,0.0002271645],"domain_scores_gemma":[0.9992604,0.00001084931,0.0001569608,0.0004205014,0.00008670367,0.00006458597],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000600533,0.00001038381,0.01167787,0.0001540543,0.00002227512,0.00003109629,0.0001487651,0.000007623702,0.9859287,0.00005177072,0.001803412,0.0001039794],"study_design_scores_gemma":[0.0006291888,0.00002391218,0.4447054,0.0002143098,0.00004954813,0.00007096283,0.0001122571,0.00003481395,0.4914812,0.00003205524,0.06233048,0.0003158844],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985836,0.0001753448,0.00002250272,0.0003764742,0.0001683424,0.0002354155,0.0002247174,0.000006086118,0.0002075085],"genre_scores_gemma":[0.997308,0.000128674,0.0001341906,0.0001085864,0.00006296878,0.000004327246,0.00005000996,0.00002280714,0.00218043],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4944475,"threshold_uncertainty_score":0.816286,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004770667183999373,"score_gpt":0.1981528441981186,"score_spread":0.1933821770141192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}