{"id":"W4321487237","doi":"10.1101/2023.02.22.529436","title":"Mucus production, host-microbiome interactions, hormone sensitivity, and innate immune responses modeled in human cervix chips","year":2023,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"Reproductive tract infections research","field":"Immunology and Microbiology","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Natural Sciences and Engineering Research Council of Canada; Hansjörg Wyss Institute for Biologically Inspired Engineering, Harvard University; Harvard University; Bill and Melinda Gates Foundation","keywords":"Mucus; Cervix; Biology; Microbiome; Epithelium; Immune system; Innate immune system; Stromal cell; Immunology; Hormone; Cell biology; Endocrinology; Bioinformatics; Cancer research; Cancer","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001944609,0.0002169386,0.0002353105,0.0001954567,0.0001341281,0.0003452029,0.0002325305,0.0003564257,0.0008442706],"category_scores_gemma":[0.000204319,0.0001661436,0.0003109397,0.0001947678,0.0002014011,0.0001435001,0.0002821209,0.0002095216,0.0001706115],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00029573,"about_ca_system_score_gemma":0.0002876252,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002223642,"about_ca_topic_score_gemma":0.002090514,"domain_scores_codex":[0.9998544,0.00002084244,0.000008514441,0.00004059159,0.00004387842,0.00003182599],"domain_scores_gemma":[0.9999014,0.00003026378,0.00002110785,0.00001476921,0.00001790559,0.0000145999],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"simulation_or_modeling","study_design_scores_codex":[0.000090291,0.00002234863,0.001945645,0.00006293896,0.00001004188,0.00008179546,0.00005309139,0.001780223,0.9943385,0.00008207058,0.00005539448,0.001477736],"study_design_scores_gemma":[0.00001701642,0.0009752269,0.03014696,0.00002770022,0.00005447305,0.0002589008,0.0003524084,0.02326379,0.9409984,0.0001190532,0.003750531,0.00003541912],"study_design_candidate":"simulation_or_modeling","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9913722,0.0006487925,0.00650976,0.00003848238,0.00001896977,0.00004022778,0.0006282756,0.00005772043,0.0006855226],"genre_scores_gemma":[0.9926597,0.0003670433,0.005506096,0.00004465149,0.000003691957,0.00007610774,0.0006132535,0.00000864288,0.0007209355],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002223642,"threshold_uncertainty_score":0.004421473,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03070661785663083,"score_gpt":0.2794277451612431,"score_spread":0.2487211273046122,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}