{"id":"W4321494879","doi":"10.1002/slct.202204076","title":"Evaluation of Neuroprotective and Adjuvant Activities of Diketopiperazine‐Based Peptidomimetics","year":2023,"lang":"en","type":"article","venue":"ChemistrySelect","topic":"RNA Interference and Gene Delivery","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hatch (Canada)","funders":"","keywords":"Peptidomimetic; Neuroprotection; Adjuvant; Chemistry; Stereochemistry; Peptide; Piperazine; Glycopeptide; Combinatorial chemistry; Pharmacology; Biochemistry; Medicine; Organic chemistry; Immunology; Antibiotics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001340002,0.0003796197,0.0002081006,0.0002049733,0.0000689869,0.0001152575,0.0001311552,0.0001543057,0.0006751624],"category_scores_gemma":[0.000102878,0.00006739388,0.000124474,0.0001593823,0.0001142029,0.0001166514,0.00006957317,0.0002471242,0.0001122664],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001716021,"about_ca_system_score_gemma":0.0001740804,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005555183,"about_ca_topic_score_gemma":0.0008152789,"domain_scores_codex":[0.9999465,0.000009897184,0.000005522014,0.000008325669,0.0000146926,0.00001520594],"domain_scores_gemma":[0.9999276,0.00001374924,0.00002007169,0.000004411941,0.00001219315,0.00002196836],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001190724,0.00005344349,0.00005926271,0.00005268056,0.000003875464,0.00002334711,0.000005468971,0.0001315555,0.9986038,0.00002677993,0.00001177951,0.0009089381],"study_design_scores_gemma":[0.00002294442,0.001341741,0.0008369024,0.000003979694,0.00001440895,0.00004912104,0.000006446031,0.0003179247,0.9969772,0.000008655474,0.000418107,0.000002636912],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996621,0.001728878,0.0007211803,0.00002334528,0.00001243846,0.00004178944,0.0001913989,0.00002138972,0.0006385698],"genre_scores_gemma":[0.9951099,0.001700668,0.001939144,0.00001674415,0.000008948277,0.00003725027,0.0002918924,0.000005372175,0.0008901363],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0006751624,"threshold_uncertainty_score":0.002258658,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02673488257312359,"score_gpt":0.2884230337447372,"score_spread":0.2616881511716136,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}