{"id":"W4321496491","doi":"10.1097/hep.0000000000000316","title":"Metabolomics as a tool to predict the risk of decompensation or liver-related death in patients with compensated cirrhosis","year":2023,"lang":"en","type":"article","venue":"Hepatology","topic":"Liver Disease and Transplantation","field":"Medicine","cited_by":12,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Decompensation; Internal medicine; Cirrhosis; Gastroenterology; Placebo; Clinical endpoint; Portal hypertension; Metabolite; Univariate analysis; Proportional hazards model; Portal venous pressure; Randomized controlled trial; Multivariate analysis; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001484755,0.0001009025,0.0002684561,0.0001873861,0.0000506748,0.000004639382,0.00006536992,0.00007731609,0.0001211269],"category_scores_gemma":[0.00005060179,0.00006051847,0.00003865524,0.0005493316,0.00004702752,0.00004531858,0.00001723604,0.0001109518,0.0001120889],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002845175,"about_ca_system_score_gemma":0.0001275054,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008692467,"about_ca_topic_score_gemma":0.0004498932,"domain_scores_codex":[0.9990763,0.0001437888,0.0002639925,0.0001827672,0.0001635141,0.0001696421],"domain_scores_gemma":[0.9993627,0.0001922849,0.00009442747,0.0001828673,0.0001117709,0.00005593048],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00261231,0.0001175519,0.9948431,0.00003959575,0.0003060742,0.00004371791,0.001093123,0.00005805106,0.00002490156,0.0002555527,0.00005133542,0.0005547046],"study_design_scores_gemma":[0.003436352,0.0006521522,0.9904163,0.00005309237,0.000761145,0.000008861316,0.00005966733,0.00401999,0.0003597916,0.00008688748,0.00007390555,0.00007184315],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986455,0.00002547824,0.00004496146,0.0001920637,0.00006460478,0.0007798504,0.00006901995,0.0000573145,0.0001211724],"genre_scores_gemma":[0.9991496,0.0001682273,0.0001099341,0.0001696546,0.00000634565,0.00003726414,0.0003005941,0.00001327495,0.00004512109],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00442677,"threshold_uncertainty_score":0.2467871,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01433635688334247,"score_gpt":0.250039094676723,"score_spread":0.2357027377933805,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}