{"id":"W4321600996","doi":"10.1002/anie.202301202","title":"Molecularly Imprinted Nanobeacons Redirect Innate Immune Killing towards Triple Negative Breast Cancer","year":2023,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Nanjing University; National Natural Science Foundation of China","keywords":"Triple-negative breast cancer; Innate immune system; Hapten; Antibody; Immunology; Cancer research; Cancer; Immunity; Immune system; Biology; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0003200129,0.0002398253,0.0002626306,0.0003029089,0.0002210671,0.00005017484,0.0003412419,0.0002418591,0.002304031],"category_scores_gemma":[0.0001792738,0.0002287978,0.0002065708,0.0004097155,0.0001768912,0.000326668,0.0001090537,0.0003529847,0.0004317075],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001936396,"about_ca_system_score_gemma":0.0001346669,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009058814,"about_ca_topic_score_gemma":0.00001388238,"domain_scores_codex":[0.9986568,0.000101491,0.0004042615,0.0003461648,0.0001220904,0.0003691679],"domain_scores_gemma":[0.9990665,0.000139889,0.0002045232,0.0001991915,0.0003673497,0.00002255304],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0007543988,0.00007307446,0.00005952228,0.000009569615,0.0005771409,0.00001289084,0.000553878,0.000005939896,0.9830574,0.00008875069,0.006890998,0.007916395],"study_design_scores_gemma":[0.001808517,0.00005008157,0.00848576,0.0001434189,0.00003452673,0.00008941884,0.0002892114,0.00003530389,0.9667072,0.000278058,0.02182985,0.000248667],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9178283,0.007908163,0.005219436,0.02025536,0.03240552,0.001104606,0.00350138,0.001548501,0.01022877],"genre_scores_gemma":[0.9854612,0.002280093,0.00004639912,0.0003199682,0.0003736243,0.0001931154,0.00167745,0.00004011847,0.00960806],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06763291,"threshold_uncertainty_score":0.998608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01358149763005757,"score_gpt":0.2710361014510528,"score_spread":0.2574546038209953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}