{"id":"W4321600996","doi":"10.1002/anie.202301202","title":"Molecularly Imprinted Nanobeacons Redirect Innate Immune Killing towards Triple Negative Breast Cancer","year":2023,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"Nanjing University; National Natural Science Foundation of China","keywords":"Triple-negative breast cancer; Innate immune system; Hapten; Antibody; Immunology; Cancer research; Cancer; Immunity; Immune system; Biology; Breast cancer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001071266,0.000274242,0.0001660318,0.0001120267,0.00007116163,0.0001719071,0.0001673914,0.000386105,0.0008454806],"category_scores_gemma":[0.0001105297,0.0001423512,0.0001725164,0.00007078722,0.0001756219,0.0002557403,0.0002093515,0.0003872361,0.0003593985],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001857586,"about_ca_system_score_gemma":0.0001230794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001815122,"about_ca_topic_score_gemma":0.0003820904,"domain_scores_codex":[0.9999251,0.00001097913,0.000003888453,0.00001507345,0.00002604185,0.00001882812],"domain_scores_gemma":[0.9999555,0.000008719049,0.00001440401,0.000003830468,0.000007597062,0.000009897858],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004892801,0.00001919823,0.00006428601,0.00009579329,0.000007818849,0.00006779229,0.00001935595,0.0002816319,0.9921961,0.0004987564,0.0002959603,0.006404394],"study_design_scores_gemma":[0.000007131169,0.0001542559,0.0002217194,0.000005354432,0.000007021568,0.0001194609,0.0000104682,0.001196333,0.9926304,0.00007445212,0.005567779,0.000005714219],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.91946,0.01758175,0.04719239,0.0008322589,0.0003534576,0.0001377028,0.0002963101,0.0005816202,0.01356448],"genre_scores_gemma":[0.9744051,0.004775301,0.01256368,0.0005292115,0.00003890639,0.00009476618,0.0001440047,0.00003894522,0.007410178],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008454806,"threshold_uncertainty_score":0.002828479,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01358149763005757,"score_gpt":0.2710361014510528,"score_spread":0.2574546038209953,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}