{"id":"W4321601109","doi":"10.1007/s11684-022-0971-9","title":"A new perspective in pyroptosis: lifting the veil on GSDMA activation","year":2023,"lang":"en","type":"article","venue":"Frontiers of Medicine","topic":"Inflammasome and immune disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"SKiN Health","funders":"","keywords":"Pyroptosis; Perspective (graphical); Psychology; Computer science; Medicine; Artificial intelligence; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002117787,0.00007825672,0.0001141522,0.00009513406,0.0000355424,0.000002200006,0.0001286425,0.00006079814,0.000008375609],"category_scores_gemma":[0.0003692617,0.00005403858,0.00003490593,0.0002434185,0.00007746176,0.000002844552,0.00003021276,0.0000858887,0.000004858608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001735778,"about_ca_system_score_gemma":0.0000497104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001977318,"about_ca_topic_score_gemma":0.0000148348,"domain_scores_codex":[0.999426,0.00003282186,0.0001398568,0.0001440285,0.0001212147,0.0001360887],"domain_scores_gemma":[0.9996745,0.00001201315,0.00006586095,0.000181304,0.00004544398,0.0000208562],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006061738,0.00004459413,0.006986336,0.00001721662,0.0001537762,0.000002693217,0.00712359,0.0003704511,0.4179393,0.0004957484,0.5339543,0.03230582],"study_design_scores_gemma":[0.009148892,0.002967158,0.1008495,0.0004085949,0.00007169721,0.000002641575,0.1660994,0.0006059423,0.5572602,0.002406248,0.1596714,0.0005083737],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9727372,0.002035503,0.0009842145,0.01760702,0.0004355978,0.0002307801,0.000001422769,0.00001601468,0.005952223],"genre_scores_gemma":[0.9978589,0.0002808735,0.00008007672,0.0004380189,0.000242453,0.000008779248,0.00003470869,0.00001132994,0.001044903],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3742829,"threshold_uncertainty_score":0.2203629,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008090768517563901,"score_gpt":0.2545239696001127,"score_spread":0.2464332010825488,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}