{"id":"W4321748991","doi":"10.1021/acschembio.2c00728","title":"Discovery and Enzymatic Screening of Genome-Mined Microbial Levanases to Produce Second-Generation β-(2,6)-Fructooligosaccharides: Catalytic Properties","year":2023,"lang":"en","type":"article","venue":"ACS Chemical Biology","topic":"Microbial Metabolites in Food Biotechnology","field":"Nursing","cited_by":8,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation","keywords":"Inulin; In silico; Hydrolysis; Chemistry; Biochemistry; Enzyme; Prebiotic; Biology; Food science; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002519433,0.000247704,0.0005005612,0.0002914341,0.0000741839,0.00003610562,0.0003416401,0.0003214799,0.00001382192],"category_scores_gemma":[0.001312562,0.0002130384,0.00005883437,0.0005530255,0.0004071773,0.0001382912,0.0004050018,0.0002172672,0.00004129226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004243184,"about_ca_system_score_gemma":0.00002571406,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005031779,"about_ca_topic_score_gemma":0.00003797256,"domain_scores_codex":[0.998207,0.00007813062,0.0005435278,0.0006188207,0.00007567295,0.0004768812],"domain_scores_gemma":[0.9991443,0.000117377,0.0001550133,0.000440477,0.000076354,0.00006643929],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001637815,0.00003050798,0.0001611296,0.0001518731,0.00004414237,0.000001382487,0.0004444235,0.000006178572,0.9944651,0.0001192887,0.0006734362,0.003738724],"study_design_scores_gemma":[0.0003455253,0.0001923907,0.0001711624,0.00004837142,0.00004500058,0.00003209192,0.00009614868,0.00005184595,0.9972148,0.0001961917,0.001360309,0.0002461669],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959902,0.0006248406,0.00008059157,0.002013283,0.0004369549,0.0005350825,0.0001464607,0.0001600265,0.00001263009],"genre_scores_gemma":[0.9970722,0.0000189674,0.001714271,0.000452436,0.0003014272,0.00003510154,0.0002680788,0.00003214888,0.000105334],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003492557,"threshold_uncertainty_score":0.8687454,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03562629641001023,"score_gpt":0.2615036194044919,"score_spread":0.2258773229944817,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}