{"id":"W4321749352","doi":"10.1167/tvst.12.2.31","title":"ALK5 Inhibition of Subconjunctival Scarring From Glaucoma Surgery: Effects of SB-431542 Compared to Mitomycin C in Human Tenon's Capsule Fibroblasts","year":2023,"lang":"en","type":"article","venue":"Translational Vision Science & Technology","topic":"Glaucoma and retinal disorders","field":"Medicine","cited_by":6,"is_retracted":false,"has_abstract":true,"ca_institutions":"Lawson Health Research Institute; University of Ottawa; St Joseph's Health Care; Western University","funders":"Schulich School of Medicine and Dentistry","keywords":"Mitomycin C; Lactate dehydrogenase; Chemistry; Cytotoxicity; MTT assay; Viability assay; Molecular biology; Fibroblast; In vitro; Pharmacology; Medicine; Biochemistry; Surgery; Biology; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002438538,0.0004434627,0.0003538836,0.0002243323,0.0001792815,0.0002431897,0.0001755823,0.0002252984,0.001927501],"category_scores_gemma":[0.0001011792,0.0001252646,0.0004144388,0.0001574722,0.0001889004,0.0001913822,0.0001351526,0.0004989789,0.0003165247],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001954533,"about_ca_system_score_gemma":0.000363678,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00131848,"about_ca_topic_score_gemma":0.002488328,"domain_scores_codex":[0.9998617,0.00003478773,0.00001792034,0.00001436837,0.00003249312,0.00003864291],"domain_scores_gemma":[0.9999042,0.00001571405,0.00001899569,0.000009792197,0.00001336922,0.00003799016],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002348643,0.0005729613,0.0005168145,0.0002294952,0.00002497626,0.0001496819,0.00004433314,0.0001103441,0.9899948,0.00004714658,0.0001565628,0.0058043],"study_design_scores_gemma":[0.0002630987,0.01353715,0.01482073,0.00002311589,0.0001167254,0.0004542286,0.0001275262,0.0007193959,0.9672346,0.00002411212,0.002668709,0.00001066521],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9938813,0.003888225,0.0003587996,0.00009158918,0.00007816203,0.00004044444,0.0001869177,0.00002760561,0.001446874],"genre_scores_gemma":[0.9942201,0.002723658,0.0004991808,0.00006003555,0.00002602061,0.000062078,0.000425482,0.00000571942,0.001977572],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001927501,"threshold_uncertainty_score":0.00644809,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01208905037267957,"score_gpt":0.2984151119134871,"score_spread":0.2863260615408075,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}