{"id":"W4321763653","doi":"10.1016/j.vaccine.2023.02.058","title":"Purification of recombinant vesicular stomatitis virus-based HIV vaccine candidate","year":2023,"lang":"en","type":"article","venue":"Vaccine","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":6,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; National Research Council Canada","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research","keywords":"Vesicular stomatitis virus; Chromatography; Ultracentrifuge; Centrifugation; Density gradient; Ultrafiltration (renal); Recombinant DNA; Filtration (mathematics); Cross-flow filtration; Virus; Size-exclusion chromatography; Chemistry; Virology; Biology; Biochemistry; Membrane; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001814792,0.0003695391,0.0003642095,0.000272891,0.0002580923,0.0003030078,0.0002710799,0.0002658967,0.001664137],"category_scores_gemma":[0.0002918193,0.0001629249,0.0003643331,0.0003883535,0.0001118876,0.0002108253,0.0001890931,0.0006849379,0.001290231],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003175527,"about_ca_system_score_gemma":0.000424303,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008098524,"about_ca_topic_score_gemma":0.001035807,"domain_scores_codex":[0.9998983,0.00001910681,0.000008089853,0.00001888016,0.00002503512,0.00003056003],"domain_scores_gemma":[0.9999393,0.00001534185,0.000006222144,0.000006223664,0.00002068523,0.00001212879],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006936061,0.00005155505,0.0002439941,0.00006340416,0.000009917798,0.00009379649,0.00003847132,0.0002488933,0.9954466,0.0003718348,0.0002803276,0.003081615],"study_design_scores_gemma":[0.0000251591,0.000193947,0.001360392,0.00001357286,0.00002717195,0.0002490124,0.00005863898,0.001782883,0.9836924,0.0001851596,0.0124035,0.000008087462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9302561,0.00368965,0.05742361,0.000779153,0.0002307272,0.0003666214,0.00232564,0.0002664162,0.004662078],"genre_scores_gemma":[0.9146566,0.002919433,0.04420362,0.000371284,0.0000581944,0.0002673962,0.01305432,0.0001173156,0.02435183],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001664137,"threshold_uncertainty_score":0.005567074,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01298152045178338,"score_gpt":0.2808283454814812,"score_spread":0.2678468250296978,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}