{"id":"W4322501852","doi":"10.3390/pharmaceutics15030767","title":"Preclinical PET Imaging and Toxicity Study of a 68Ga-Functionalized Polymeric Cardiac Blood Pool Agent","year":2023,"lang":"en","type":"article","venue":"Pharmaceutics","topic":"Radiopharmaceutical Chemistry and Applications","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"Canadian Institutes of Health Research","keywords":"Biodistribution; Toxicity; Nuclear medicine; Medicine; Imaging agent; Cardiac toxicity; Pet imaging; Biomedical engineering; Chemistry; Positron emission tomography; Internal medicine; In vivo; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003205786,0.0001529995,0.0003321932,0.0000601238,0.0000981938,0.00001211048,0.00008312291,0.00002032049,0.0001774829],"category_scores_gemma":[0.0001126896,0.0001443062,0.0001008674,0.0004474714,0.0001211105,0.0000390662,0.00009749758,0.0002828926,0.00002407138],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001990814,"about_ca_system_score_gemma":0.00005399215,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000007500653,"about_ca_topic_score_gemma":1.210696e-7,"domain_scores_codex":[0.9986641,0.00006833716,0.0003852387,0.0003187314,0.0003160264,0.0002475395],"domain_scores_gemma":[0.9990379,0.0002601572,0.00008541783,0.000255321,0.00007267074,0.0002884892],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0006652903,0.00464898,0.17769,0.0005673149,0.001220435,0.0002667432,0.0006729568,0.00006241206,0.7951199,0.00007838951,0.002174156,0.01683342],"study_design_scores_gemma":[0.02119651,0.000617274,0.142835,0.0001268519,0.007872305,0.0005769599,0.002312268,0.03234967,0.7412961,0.0001952939,0.04977648,0.0008453058],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959501,0.0008026908,0.00002434079,0.001236694,0.0001423958,0.0006298349,0.0000420636,0.0001452535,0.001026621],"genre_scores_gemma":[0.997909,0.0006287015,0.00009333876,0.0003903781,0.0002110636,0.00009066868,0.00003065831,0.00002171258,0.0006244691],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05382381,"threshold_uncertainty_score":0.5884637,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08938839876072333,"score_gpt":0.4219149979119917,"score_spread":0.3325265991512684,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}