{"id":"W4322502728","doi":"10.3390/ph16030349","title":"Functionalized Lipid Nanocarriers for Simultaneous Delivery of Docetaxel and Tariquidar to Chemoresistant Cancer Cells","year":2023,"lang":"en","type":"article","venue":"Pharmaceuticals","topic":"Nanoparticle-Based Drug Delivery","field":"Materials Science","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"York University","funders":"Ministry of Science and ICT, South Korea; National Research Foundation of Korea; Chung-Ang University; National Research Foundation","keywords":"Nanocarriers; Docetaxel; Cytotoxicity; Drug delivery; Pharmacology; Chemistry; Materials science; In vitro; Medicine; Nanotechnology; Cancer; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001571982,0.0003459901,0.000317609,0.0002100665,0.0001295823,0.0002535088,0.0001952109,0.0003464668,0.0004532125],"category_scores_gemma":[0.0001447235,0.0001460603,0.0002840618,0.0001590837,0.0001590417,0.000306801,0.0002607915,0.0003036547,0.0002807918],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006473221,"about_ca_system_score_gemma":0.0003301134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001023323,"about_ca_topic_score_gemma":0.001333212,"domain_scores_codex":[0.9998698,0.00001545982,0.00001325698,0.00003759221,0.00004011834,0.00002371187],"domain_scores_gemma":[0.9999397,0.000008805801,0.00002034808,0.0000052869,0.00001508546,0.0000107133],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004048179,0.000009051678,0.00002851995,0.00002075072,0.000003406904,0.00002173142,0.0000102589,0.0001460177,0.9985267,0.00007290524,0.00001530459,0.001104886],"study_design_scores_gemma":[0.00001613842,0.0001454995,0.0002054443,0.000002570671,0.00001654486,0.00008047586,0.000006362678,0.001504333,0.9967285,0.0000165673,0.001271625,0.000005852619],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9841955,0.001980589,0.01199758,0.0001210313,0.00004758903,0.00009060098,0.0001837218,0.0001438596,0.001239508],"genre_scores_gemma":[0.9827389,0.001087837,0.01382246,0.0000652216,0.00001466763,0.00008896213,0.0001985145,0.00003011432,0.001953338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001023323,"threshold_uncertainty_score":0.004696667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03671918207111295,"score_gpt":0.3304520314852541,"score_spread":0.2937328494141411,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}