{"id":"W4322504764","doi":"10.1038/s41598-023-30016-0","title":"E-liquid alters oral epithelial cell function to promote epithelial to mesenchymal transition and invasiveness in preclinical oral squamous cell carcinoma","year":2023,"lang":"en","type":"article","venue":"Scientific Reports","topic":"Oral Health Pathology and Treatment","field":"Dentistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Fonds de Recherche du Québec - Santé; Jewish General Hospital; Réseau de Recherche en Santé Buccodentaire et Osseuse; Canadian Bureau for International Education; Canadian Institutes of Health Research; Coordenação de Aperfeiçoamento de Pessoal de Nível Superior; McGill University; Helsingin Yliopisto","keywords":"Epithelial–mesenchymal transition; Vimentin; Carcinogenesis; Cancer research; Cell growth; Cell culture; Mesenchymal stem cell; Epithelium; Cell; Biology; Cell biology; Cancer; Pathology; Immunology; Medicine; Metastasis; Immunohistochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004285114,0.0003996973,0.000445259,0.0005165211,0.000207705,0.0003538347,0.0002829943,0.0004234294,0.002025556],"category_scores_gemma":[0.0001649959,0.0002233627,0.0005032852,0.0002873366,0.0003166026,0.0003449525,0.0001839036,0.0008604488,0.0004984518],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002744262,"about_ca_system_score_gemma":0.0004361379,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00076546,"about_ca_topic_score_gemma":0.001429813,"domain_scores_codex":[0.9997261,0.00006712355,0.00003344717,0.00002187544,0.00006882059,0.00008259054],"domain_scores_gemma":[0.9998472,0.0000256081,0.00002935032,0.00002374399,0.00002743683,0.00004677513],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001337634,0.002537204,0.0009457785,0.0000831014,0.00001837667,0.0001533534,0.00005104464,0.0002072887,0.9910631,0.0001180823,0.0001473332,0.003337652],"study_design_scores_gemma":[0.000203271,0.01688305,0.0140572,0.00001879454,0.00008748641,0.0002476441,0.0002514029,0.001356186,0.963845,0.0000946559,0.002941779,0.00001356709],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9971859,0.0007353147,0.0005947892,0.00006937672,0.00002749973,0.00009761215,0.0002643881,0.0000385198,0.0009865937],"genre_scores_gemma":[0.9948665,0.0008947254,0.0006719179,0.00006649992,0.000008025137,0.000131864,0.0005449728,0.0000107679,0.002804576],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002025556,"threshold_uncertainty_score":0.006776094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04229110333101538,"score_gpt":0.3250371430897114,"score_spread":0.282746039758696,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}